⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127037 | 0.77 | — | — | |
| SCHEMBL6177602 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL25395630 | 0.73 | SCN4A (0.35) | — | |
| SCHEMBL25394122 | 0.73 | SCN4A (0.35) | — | |
| SCHEMBL129174 | 0.71 | — | — | |
| SCHEMBL128483 | 0.71 | — | — | |
| SCHEMBL4198665 | 0.69 | — | — | |
| SCHEMBL25812 | 0.69 | — | — | |
| SCHEMBL20485768 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL1476921 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215505-B1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10118930-B2 | Piperidinylpyrazolopyrimidinones and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-06 | — | — | US | disclosed |
| US-20170334917-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3215505-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | Bayer Pharma Aktiengesellschaft (DE) | 2017-09-13 | — | — | EP | disclosed |
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016173948-A1 | INDAZOLOPYRIMIDINONES AS FIBRINOLYSIS INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-11-03 | — | — | WO | disclosed |
| EP-1655291-B1 | COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM | SHIONOGI & CO (JP) | 2016-08-03 | — | — | EP | disclosed |
| WO-2016087593-A1 | NOVEL FUNGICIDAL QUINOLINYLAMIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016071216-A1 | PIPERIDINYLPYRAZOLOPYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| CN-103130739-B | There is the compound of thrombopoietin receptor agonism | SHIONOGI & CO., LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| US-5064818-A | PESTICIDAL PYRIMIDINYL (THIONO) (THIO)-PHOSPHORIC (PHOSPHONIC)ACID (AMIDE) ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-12 | — | — | US | disclosed |
| EP-0395968-A1 | (Thiono) (thio)pyrimidyl-phosphonyl (phosphonic) ester (amid) | BAYER AG (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0213377-B1 | PHOSPHORIC (PHOSPHONIC) ACID ESTERS | BAYER AG (DE) | 1989-02-15 | — | — | EP | disclosed |
| EP-0222255-A2 | Mixtures of blue disperse dyes and their use in dyeing polyesters | CASSELLA Aktiengesellschaft (DE) | 1987-05-20 | — | — | EP | disclosed |
| EP-0213377-A1 | Phosphoric (phosphonic) acid esters | BAYER AG (DE) | 1987-03-11 | — | — | EP | disclosed |
| US-4623655-A | Fungicidal iminomethyl-azolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-18 | — | — | US | disclosed |
| EP-0173857-A1 | Fungicidal agent based on phosphoryloximinoacetamide | BAYER AG (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0146105-A2 | Iminomethyl-azolyl derivatives | BAYER AG (DE) | 1985-06-26 | — | — | EP | disclosed |
| EP-0132676-A2 | Phosphoric or phosphonic acid esters | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0100476-A2 | Phosphoric-acid esters, process for their preparation and their use as pesticides | BAYER AG (DE) | 1984-02-15 | — | — | EP | disclosed |