Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196449 | 0.83 | KDM4E (0.47) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL29287448 | 0.83 | MAPT (0.38) | IKBKBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL12970754 | 0.82 | ALDH1A1 (0.38) | IKBKBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4116744 | 0.78 | KDM4E (0.50) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11004280 | 0.78 | SIRT3 (0.47) | IKBKBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL4806709 | 0.77 | KMT2A (0.41) | MAPTALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL5777262 | 0.77 | ERN1 (0.38) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL1476008 | 0.77 | DGAT1 (0.41) | IKBKBMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL1196349 | 0.76 | ALDH1A1 (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28406195 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1KMT2AMEN1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086911-B | Oligomer, polyimide film/fiber containing oligomer and preparation method of polyimide film/fiber containing oligomer | UNIV SICHUAN | 2014-09-03 | — | — | CN | claimed |
| CN-102677225-B | Aromatic polyamide/aromatic polyimide blended fiber and preparation method thereof | UNIV SICHUAN | 2014-03-12 | — | — | CN | claimed |
| CN-103086911-A | Oligomer, polyimide film/fiber containing oligomer and preparation method of polyimide film/fiber containing oligomer | UNIV SICHUAN | 2013-05-08 | — | — | CN | claimed |
| EP-1592667-A2 | NEW MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-09 | — | — | EP | claimed |
| WO-2004069803-A2 | MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES AND THEIR USE AGAINST CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-19 | — | — | WO | claimed |
| CN-102677225-B | Aromatic polyamide/aromatic polyimide blended fiber and preparation method thereof | UNIV SICHUAN | 2014-03-12 | — | — | CN | disclosed |
| US-7501451-B2 | Mono-acylated o-phenylendiamines derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-7071219-B2 | Mono-acylated o-phenylendiamines derivatives | HOFFMANN-LA ROCHE INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20060089403-A1 | Mono-acylated o-phenylendiamines derivatives | FERTIG GEORG | 2006-04-27 | — | — | US | disclosed |
| EP-1592667-A2 | NEW MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069803-A2 | MONO-ACYLATED O-PHENYLENDIAMINES DERIVATIVES AND THEIR USE AGAINST CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089403-A1 | Mono-acylated o-phenylendiamines derivatives | HDAC1, HDAC10, HDAC11 | IKBKB 2764/4885MAPT 2800/4885ALDH1A1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.