Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.46 |
| ▸ | PTP4A2 | Q12974 | 2/20 | 0.46 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488546 | 1.00 | APP (0.52) | APPDNM1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4481016 | 0.88 | PKM (0.54) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4481022 | 0.88 | PKM (0.54) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13678150 | 0.88 | CYP1A2 (0.51) | APPDNM1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6028926 | 0.86 | MCL1 (0.56) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6028927 | 0.86 | MCL1 (0.56) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4485253 | 0.85 | DNM1 (0.48) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4485259 | 0.85 | DNM1 (0.48) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4487740 | 0.83 | DNM1 (0.46) | DNM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1552128 | 0.82 | PTP4A3 (0.44) | APPDNM1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272457-B9 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RES DEV LP (CA) | 2006-12-20 | — | — | EP | claimed |
| EP-1272457-B1 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RES DEV LP (CA) | 2006-08-23 | — | — | EP | claimed |
| US-7012095-B2 | Compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED (CA) | 2006-03-14 | — | — | US | claimed |
| US-20040209845-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2004-10-21 | — | — | US | claimed |
| US-20040072803-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED (CA) | 2004-04-15 | — | — | US | claimed |
| JP-2003531133-A | — | — | 2003-10-21 | — | — | JP | claimed |
| US-20030109502-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2003-06-12 | — | — | US | claimed |
| EP-1272457-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC Research and Development Limited Partnership (CA) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079158-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2001-10-25 | — | — | WO | claimed |
| US-7598419-B2 | Compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2009-10-06 | — | — | US | disclosed |
| US-20070243612-A1 | Novel Compounds for Modulating Cell Proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2007-10-18 | — | — | US | disclosed |
| EP-1727822-A4 | NOVEL COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RES DEV LP (CA) | 2007-05-09 | — | — | EP | disclosed |
| EP-1752446-A2 | Compounds for modulating cell proliferation | HSC Research and Development Limited Partnership (CA) | 2007-02-14 | — | — | EP | disclosed |
| EP-1272457-B9 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RES DEV LP (CA) | 2006-12-20 | — | — | EP | disclosed |
| US-20040209845-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2004-10-21 | — | — | US | disclosed |
| US-6800659-B2 | NOVEL STYRYLACRYLONITRILE COMPOUNDS WHICH ARE USEFUL IN TREATING A VARIETY OF CELL PROLIFERATIVE DISORDERS SUCH AS CANCER ARE DISCLOSED. A METHOD OF MODULATING CELL PROLIFERATION COMPRISING ADMINISTERING AN EFFECTIVE AMOUNT OF | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2004-10-05 | — | — | US | disclosed |
| US-20040072803-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED (CA) | 2004-04-15 | — | — | US | disclosed |
| US-20030109502-A1 | Novel compounds for modulating cell proliferation | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2003-06-12 | — | — | US | disclosed |
| EP-1272457-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC Research and Development Limited Partnership (CA) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079158-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070243612-A1 | Novel Compounds for Modulating Cell Proliferation | MKI67, CCNA1, PCNA | APP 4723/4885DNM1 2951/4885CYP1A2 4684/4885 |
| US-20040209845-A1 | Novel compounds for modulating cell proliferation | MKI67, CCNA1, CCNI | APP 4671/4885DNM1 2447/4885CYP1A2 4071/4885 |
| US-20030109502-A1 | Novel compounds for modulating cell proliferation | MKI67, CCNA1, CCNI | APP 4671/4885DNM1 2447/4885CYP1A2 4071/4885 |
| US-20040072803-A1 | Novel compounds for modulating cell proliferation | MKI67, CCNA1, MCL1 | APP 4607/4885DNM1 2566/4885CYP1A2 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.