SCHEMBL448863

SCHEMBL448863

CCCCCCCCCCCCN(CCCCCCCCCCCC)C(=S)SSC(=S)N(CCCCCCCCCCCC)CCCCCCCCCCCC

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.84
ALDH1A1 P00352 5/20 0.83
ALDH2 P05091 4/20 0.83
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA9 Q16790 3/20 0.59
TSHR P16473 2/20 0.52
PKM P14618 2/20 0.52
PHGDH O43175 1/20 0.52
PLIN1 O60240 1/20 0.52
GMNN O75496 1/20 0.52
TRPA1 O75762 1/20 0.52
ABCB11 O95342 1/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
HSP90AA1 P07900 1/20 0.52
CYP3A4 P08684 1/20 0.52
HTR1A P08908 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11010068 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL6417261 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL15158100 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL284494 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL15157784 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL8468348 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL5410089 1.00 MGLL (0.84) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL11014268 0.98 ALDH1A1 (0.87) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL283865 0.98 ALDH1A1 (0.86) MGLLALDH1A1ALDH2CA12CA1
SCHEMBL24360190 0.95 ALDH1A1 (0.91) MGLLALDH1A1ALDH2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534599-B2 Rubber composition for base tread and tire BRIDGESTONE CORPORATION (JP) 2026-01-27 US disclosed
WO-2025262619-A1 RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2025-12-26 WO disclosed
EP-4667236-A1 RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2025-12-24 EP disclosed
WO-2025242722-A1 VEHICLE TIRE COMPOSITIONS COMPRISING GRANULATED SILICA AND MICRO PEARL SILICA BRIDGESTONE EUROPE NV/SA (BE) 2025-11-27 WO disclosed
US-12448474-B2 Rubber composition and tire BRIDGESTONE CORPORATION (JP) 2025-10-21 US disclosed
US-12415872-B2 Rubber composition and tire BRIDGESTONE CORPORATION (JP) 2025-09-16 US disclosed
WO-2025134061-A1 VEHICLE TIRE COMPOSITIONS COMPRISING RICE HUSK ASH SILICA BRIDGESTONE EUROPE NV/SA (BE) 2025-06-26 WO disclosed
WO-2025134059-A1 VEHICLE TIRE COMPOSITIONS COMPRISING RICE HUSK ASH SILICA BRIDGESTONE EUROPE NV/SA (BE) 2025-06-26 WO disclosed
WO-2025134065-A1 VEHICLE TIRE COMPOSITIONS COMPRISING RICE HUSK ASH SILICA BRIDGESTONE EUROPE NV/SA (BE) 2025-06-26 WO disclosed
EP-4574448-A1 VEHICLE TIRE COMPOSITIONS COMPRISING RICE HUSK ASH SILICA Bridgestone Europe NV/SA (BE) 2025-06-25 EP disclosed
US-7060757-B2 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION (JP) 2006-06-13 US disclosed
US-20040220351-A1 Rubber composition and pneumatic tire using the same BRIDGESTONE CORPORATION 2004-11-04 US disclosed
EP-1445277-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME BRIDGESTONE CORPORATION (JP) 2004-08-11 EP disclosed
US-5965640-A A CROSSLINKABLE ACRYLIC RUBBER COMPRISES A HALOGEN CONTAINING ACRYLIC RUBBER, A TRIAZINE THIOL, DITHIOCARBAMINE ACID DERIVATIVE OR THIURAM SULFIDE OR BOTH, AN AROMATIC CARBOXYLIC ACID OR AN ACID ANHYDRIDE, WHITE FILLER AND SILANE COUPLER JSR CORPORATION (JP) 1999-10-12 US disclosed
EP-0811659-A2 Acrylic rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-10 EP disclosed
EP-0376213-B1 Thermoplastic elastomer SHOWA DENKO KK (JP) 1994-03-02 EP disclosed
US-4985502-A BLEND OF POLYOLEFIN AND ETHYLENE-PROPYLENE COPOLYMER OR EPDM TERPOLYMER, FLUIDITY, STRENGTH, FLEXIBILITY SHOWA DENKO K.K. (JP) 1991-01-15 US disclosed
EP-0376213-A2 Thermoplastic elastomer SHOWA DENKO KABUSHIKI KAISHA (JP) 1990-07-04 EP disclosed
US-4006140-A AGING RESISTANCE IMPROVERS FOR VULCANIZABLE RUBBERS THE B. F. GOODRICH COMPANY (US) 1977-02-01 US disclosed
US-3852354-A HIGHER ALKYL THIUROM SULFIDE SUMITOMO CHEMICAL CO 1974-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534599-B2 Rubber composition for base tread and tire RAE1, TCEA1, TBCD MGLL 4563/4885ALDH1A1 1381/4885ALDH2 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.