⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15621595 | 0.69 | HSP90AA1 (0.51) | — | |
| SCHEMBL446362 | 0.64 | HSP90AA1 (0.63) | — | |
| SCHEMBL10231455 | 0.64 | HSP90AA1 (0.46) | — | |
| SCHEMBL465316 | 0.63 | — | — | |
| SCHEMBL12216041 | 0.63 | HSP90AA1 (0.47) | — | |
| SCHEMBL28815491 | 0.61 | — | — | |
| SCHEMBL28434498 | 0.59 | ALDH1A1 (0.38) | — | |
| SCHEMBL28436330 | 0.59 | MGAM (0.39) | — | |
| SCHEMBL27540395 | 0.58 | — | — | |
| SCHEMBL30022589 | 0.58 | MGAM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680100-B2 | Sulfonylhydrazide compounds for treating proliferative disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2014-03-25 | — | — | US | disclosed |
| US-8680100-B2 | Sulfonylhydrazide compounds for treating proliferative disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120065206-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065206-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2012-03-15 | — | — | US | disclosed |