Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GLB1 | P16278 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171353 | 0.98 | LMNA (0.74) | LMNAPOLBCYP2D6CA12CA2 | |
| SCHEMBL4808253 | 0.98 | LMNA (0.74) | LMNAPOLBCYP2D6CA12CA2 | |
| SCHEMBL28560987 | 0.89 | POLB (0.83) | LMNAPOLBCYP2D6CA12CA2 | |
| SCHEMBL18624977 | 0.89 | POLB (0.83) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL2518117 | 0.87 | LMNA (0.94) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL125057 | 0.87 | LMNA (0.94) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL11198880 | 0.84 | LMNA (0.90) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL710821 | 0.84 | LMNA (0.90) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL11202640 | 0.84 | LMNA (0.90) | LMNAPOLBCYP2D6CA12CA2 | |
| Phenolsulfonic Acid SCHEMBL10622999 | 0.84 | LMNA (1.00) | LMNAPOLBCYP2D6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069062-A2 | CHEMICALLY-DIRECTED ELECTROSTATIC SELF-ASSEMBLY OF MATERIALS | The President and Fellows of Harvard College (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080261006-A1 | Chemically-directed electrostatic self-assembly of materials | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2008-10-23 | — | — | US | disclosed |
| WO-2008045745-A2 | CHEMICALLY-DIRECTED ELECTROSTATIC SELF-ASSEMBLY OF MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-04-17 | — | — | WO | disclosed |