SCHEMBL4489557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4484659	0.86	TRPA1 (0.52)	CYP2C9SCN9ATRPA1CYP1A2
	SCHEMBL13754837	0.81	TRPA1 (0.50)	CYP2C9SCN9ATRPA1CYP1A2MAPK14
	SCHEMBL4564282	0.80	SCN9A (0.50)	CYP2C9SCN9AABCC8KCNJ11ALOX5AP
	SCHEMBL4495572	0.77	ALOX5AP (0.42)	CYP2C9SCN9AABCC8KCNJ11ALOX5AP
	SCHEMBL25011712	0.75	CYP2C9 (0.50)	CYP2C9SCN9AALOX5APFEN1CYP3A4
	SCHEMBL1041002	0.75	HDAC3 (0.55)	HDAC3HDAC6NCOR2
	SCHEMBL1400156	0.72	SCN9A (0.60)	CYP2C9SCN9ATRPA1CYP3A4CYP2D6
	SCHEMBL13754839	0.72	BRD4 (0.53)	SCN9AALOX5APFEN1KDRSCN5A
	SCHEMBL24017179	0.72	SCN9A (0.44)	CYP2C9SCN9AALOX5APFEN1EDNRB
	SCHEMBL25407073	0.72	IKBKB (0.49)	CYP2C9IKBKBCYP1A2IDO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.