Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499877 | 0.91 | ALDH1A1 (0.40) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4506359 | 0.83 | HTR2C (0.47) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4490087 | 0.83 | HTR2C (0.47) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13606372 | 0.81 | HTR2C (0.45) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4502692 | 0.81 | HTR2C (0.54) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4511725 | 0.80 | HTR2C (0.38) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4499873 | 0.74 | ALDH1A1 (0.40) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13606379 | 0.74 | ALDH1A1 (0.40) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13606374 | 0.74 | ALDH1A1 (0.40) | HTR2CKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL13606380 | 0.73 | HTR2C (0.42) | HTR2CKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |
| US-20050187224-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187224-A1 | Pyrazolopyrimidines | P2RX5, P2RX4, P2RX1 | HTR2C 993/4885KDM4E 2400/4885ALDH1A1 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.