SCHEMBL449035

SCHEMBL449035

CC(C(=O)O)=C(O)CC(C)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.32
GRIK1 P39086 1/20 0.31
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30
FNTA P49354 1/20 0.30
FNTB P49356 1/20 0.30
PGGT1B P53609 1/20 0.30
TET2 Q6N021 3/20 0.30
TET3 O43151 1/20 0.30
TET1 Q8NFU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670991 0.82 ALDH1A1 (0.50) TDP1ALDH1A1GRIK1
SCHEMBL670992 0.82 ALDH1A1 (0.50) TDP1ALDH1A1GRIK1
SCHEMBL8669803 0.80 TDP1 (0.36) TDP1ALDH1A1TP53SLC22A6GRIK1
SCHEMBL3272877 0.80 TDP1 (0.36) TDP1ALDH1A1TP53SLC22A6GRIK1
SCHEMBL8024097 0.78 ALDH1A1 (0.35) TDP1ALDH1A1GRIK1
SCHEMBL5104397 0.76 ALDH1A1 (0.39) TDP1ALDH1A1TP53GRIK1
SCHEMBL445325 0.76 ALDH1A1 (0.33) TDP1ALDH1A1TP53TSHR
SCHEMBL8601515 0.76 SLC22A6 (0.35) SLC22A6THRBFNTAFNTBPGGT1B
SCHEMBL8977483 0.76 ALDH1A1 (0.33) TDP1ALDH1A1THRBFNTAFNTB
SCHEMBL3689722 0.76 ALDH1A1 (0.33) TDP1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
US-11891469-B2 Urethane acrylate composition STRATASYS, INC. (US) 2024-02-06 US claimed
WO-2023278201-A1 NOVEL DUAL CURE 3D PRINTING RESINS COVESTRO LLC (US) 2023-01-05 WO claimed
WO-2023278202-A1 NOVEL URETHANE ACRYLATE COMPOSITION COVESTRO LLC (US) 2023-01-05 WO claimed
US-20220411563-A1 NOVEL DUAL CURE 3D PRINTING RESINS STRATASYS INC. 2022-12-29 US claimed
US-20220411560-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS INC. 2022-12-29 US claimed
US-20240166787-A1 COMPOSITIONS, POLYMERIC FILMS, AND ARTICLES INCLUDING A CHEMICAL BLOWING AGENT AND/OR A CROSSLINKER HAVING A PHOTODEGRADABLE LINKAGE, FOAM COMPOSITIONS, METHODS, AND CROSSLINKERS 3M INNOVATIVE PROPERTIES COMPANY 2024-05-23 US disclosed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP disclosed
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP disclosed
US-11904031-B2 Orthodontic articles comprising polymerized composition comprising at least two free-radical initiators 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-20 US disclosed
US-11891469-B2 Urethane acrylate composition STRATASYS, INC. (US) 2024-02-06 US disclosed
US-20230355352-A1 ARTICLES, METHODS AND COMPOSITIONS COMPRISING POLYMERIZABLE DICARBONYL POLYMERS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2023-11-09 US disclosed
US-7282272-B2 Polymerizable compositions comprising nanoparticles 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-10-16 US disclosed
US-20070112097-A1 BRIGHTNESS ENHANCING FILM AND METHODS OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 US disclosed
US-20060204676-A1 Polymerizable composition comprising low molecular weight organic component 3M INNOVATIVE PROPERTIES COMPANY 2006-09-14 US disclosed
US-20060187366-A1 MICROSTRUCTURED ARTICLE COMPRISING A POLYMERIZED COMPOSITION HAVING LOW GLASS TRANSITION TEMPERATURE 3M INNOVATIVE PROPERTIES COMPANY 2006-08-24 US disclosed
US-20050200278-A1 Polymerizable compositions comprising nanoparticles 3M INNOVATIVE PROPERTIES COMPANY 2005-09-15 US disclosed
US-20050147838-A1 Polymerizable compositions for optical articles 3M INNOVATIVE PROPERTIES COMPANY 2005-07-07 US disclosed
US-20050124713-A1 Brightness enhancing film composition 3M INNOVATIVE PROPERTIES COMPANY 2005-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11904031-B2 Orthodontic articles comprising polymerized composition comprising at least two free-radical initiators ELL, PAM, HDAC10 TDP1 3617/4885ALDH1A1 572/4885TP53 4671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.