Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500729 | 0.87 | HRH3 (0.65) | HRH3EPHX2HTR2ADRD2MAPT | |
| Oxalic Acid SCHEMBL4497957 | 0.84 | HRH3 (0.61) | HRH3HTR2ADRD2MAPT | |
| SCHEMBL4502312 | 0.84 | HRH3 (0.61) | HRH3EPHX2DRD2 | |
| SCHEMBL4622216 | 0.84 | HRH3 (0.61) | HRH3EPHX2HTR2ADRD2 | |
| SCHEMBL4485900 | 0.84 | HRH3 (0.63) | HRH3EPHX2MAPT | |
| SCHEMBL4487976 | 0.84 | HRH3 (0.63) | HRH3EPHX2MAPT | |
| SCHEMBL4622474 | 0.83 | HRH3 (0.60) | HRH3EPHX2MAPT | |
| SCHEMBL4489369 | 0.82 | HRH3 (0.72) | HRH3 | |
| SCHEMBL1978870 | 0.82 | DRD2 (0.60) | HRH3HTR2ADRD2MAPT | |
| SCHEMBL4489678 | 0.82 | HRH3 (0.61) | HRH3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576120-B2 | Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2009-08-18 | — | — | US | disclosed |
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |
| US-20070197625-A1 | Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them. | LES LABORATORATIES SERVIER (FR) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197625-A1 | Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them. | HRH2, HNMT, HRH1 | HRH3 9/4885EPHX2 446/4885HTR2A 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.