SCHEMBL449045

SCHEMBL449045

C=C(CN=C=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346413 0.76 TET2 (0.37)
SCHEMBL27982477 0.76
SCHEMBL25934862 0.75
SCHEMBL28015922 0.73 ALDH1A1 (0.39)
SCHEMBL15427 0.73 TET2 (0.39)
SCHEMBL705439 0.73
SCHEMBL30712357 0.72 TET2 (0.33)
SCHEMBL33514 0.72 TBXAS1 (0.36)
Water SCHEMBL27851057 0.70
Water SCHEMBL27336036 0.70 SLC22A6 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4824919-A ENDCAPPED POLYETHERS, ACRYLATED RESINS; FLEXIBILITY, LIGHTWEIGHT, CHEMICAL RESISTANCE THE DOW CHEMICAL COMPANY (US) 1989-04-25 US claimed
EP-3844199-B1 CURABLE TWO-COMPONENT MASS DELO INDUSTRIE KLEBSTOFFE GMBH & CO KGAA (DE) 2026-01-28 EP disclosed
US-12246345-B2 Method of forming a coating on a substrate AXALTA COATING SYSTEMS IP CO., LLC (US) 2025-03-11 US disclosed
CN-119361827-A Electrolyte additive and application thereof 蓝固(常州)新能源有限公司 2025-01-24 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
CN-113150007-B Photochromic indeno-fused ring pyran compounds 光学转变公司 2024-03-08 CN disclosed
US-11834540-B2 Curable two-component mass DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) 2023-12-05 US disclosed
CN-116613380-B Positive electrode film forming additive, preparation method thereof, electrolyte and lithium ion battery 蓝固(常州)新能源有限公司 2023-09-22 CN disclosed
CN-116613380-A Positive electrode film forming additive, preparation method thereof, electrolyte and lithium ion battery 蓝固(常州)新能源有限公司 2023-08-18 CN disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
WO-2001005578-A1 THERMOFORMABLE OPHTHALMIC LENS WESLEY-JESSEN CORPORATION (US) 2001-01-25 WO disclosed
US-5554662-A POLYMERIZATION IN PRESENCE OF BASE POLYOL, MACROMER, AND ENOL ETHER BAYER ADTIENGESELLSCHAFT (DE) 1996-09-10 US disclosed
US-5455087-A Cured acrylated polymer; high strength, hardness ENSIGN BICKFORD OPTICS COMPANY (US) 1995-10-03 US disclosed
US-5085975-A RADIATION SENSITIVE COMPOSITION UTILIZING ETHYLENICALLY UNSATURATED PERFLUOROALKYL GROUP-CONTAINING COMPOUNDS AND REPRODUCTION LAYERS PRODUCED THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0250591-A4 LOW VISCOSITY, HIGH SOLIDS POLYMER POLYOLS PREPARED USING A PREFORMED DISPERSANT 1990-09-12 EP disclosed
US-4745153-A WHICH IS (HOMO- OR CO-) POLYMER OF VINYL-TERMINATED ADDUCT OF A POLYOL THE DOW CHEMICAL COMPANY (US) 1988-05-17 US disclosed
US-4742097-A ISOCYANATES THE GLIDDEN COMPANY (US) 1988-05-03 US disclosed
EP-0250591-A1 LOW VISCOSITY, HIGH SOLIDS POLYMER POLYOLS PREPARED USING A PREFORMED DISPERSANT THE DOW CHEMICAL COMPANY (US) 1988-01-07 EP disclosed
WO-1987003886-A1 LOW VISCOSITY, HIGH SOLIDS POLYMER POLYOLS PREPARED USING A PREFORMED DISPERSANT THE DOW CHEMICAL COMPANY (US) 1987-07-02 WO disclosed
US-4639299-A LOW TEMPERATURE CURABLE SCM CORPORATION (US) 1987-01-27 US disclosed