Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491155 | 0.88 | CYP19A1 (0.46) | CYP17A1CYP19A1ALDH1A1ALOX15KMT2A | |
| SCHEMBL27847151 | 0.86 | CYP17A1 (0.45) | CYP17A1CYP19A1KDM4EKCNA5SLC6A2 | |
| SCHEMBL3109184 | 0.84 | KCNA5 (0.43) | CYP17A1CYP19A1ALDH1A1KCNA5NPSR1 | |
| SCHEMBL3114013 | 0.81 | ALOX15 (0.49) | ALDH1A1USP2KDM4EKCNA5ALOX15 | |
| SCHEMBL4485293 | 0.80 | CTSA (0.47) | — | |
| SCHEMBL3103613 | 0.78 | KCNA5 (0.40) | CYP17A1CYP19A1KCNA5SMN1; SMN2 | |
| SCHEMBL3109439 | 0.78 | NPC1 (0.49) | ALDH1A1USP2KDM4EKCNA5ALOX15 | |
| SCHEMBL3103797 | 0.77 | KCNA5 (0.40) | CYP19A1ALDH1A1USP2KDM4EKCNA5 | |
| SCHEMBL3101570 | 0.77 | HPGD (0.47) | CYP19A1ALDH1A1USP2KDM4ENPSR1 | |
| SCHEMBL27828436 | 0.76 | PLA2G7 (0.41) | CYP17A1CYP19A1KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541472-B2 | 3-Aryl-3-hydroxy-2-methylenepropionic acid esters as fungicides | CROPSOLUTION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| WO-2005115148-A1 | 3-ARYL-3-HYDROXY-2-METHYLENEPROPIONIC ACID ESTERS AS FUNGICIDES | CROPSOLUTION, INC. (US) | 2005-12-08 | — | — | WO | disclosed |