SCHEMBL449071

SCHEMBL449071

CC(COOC(C)(C)C)c1cccc(C(C)COOC(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.35
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TAAR1 Q96RJ0 2/20 0.31
CASR P41180 1/20 0.30
CACNA1F O60840 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
ADRA2B P18089 1/20 0.30
CHRM3 P20309 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
OPRK1 P41145 1/20 0.30
CACNA1D Q01668 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30
CACNA1S Q13698 1/20 0.30
CACNA1C Q13936 1/20 0.30
SCN5A Q14524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4074326 0.95 HDAC4 (0.37) RIPK1HDAC4HDAC2HDAC8CASR
SCHEMBL7933687 0.92 RIPK1 (0.31) RIPK1HDAC4HDAC2HDAC8
SCHEMBL4664725 0.89
SCHEMBL449053 0.88
SCHEMBL17710275 0.88 MAPK1 (0.49) RIPK1TAAR1CASRCACNA1FCHRM2
SCHEMBL30801347 0.87 KDM4E (0.33) RIPK1CASR
SCHEMBL1077953 0.87 RIPK1 (0.48) RIPK1TAAR1CASRCACNA1FCHRM2
SCHEMBL7937714 0.84 HDAC4 (0.35) RIPK1HDAC4HDAC2HDAC8
SCHEMBL361156 0.84 RIPK1 (0.35) RIPK1TAAR1
SCHEMBL2482298 0.83 GBA1 (0.37) HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652226-A1 MODIFIED BROMINATED POLYSTYRENES AS COMPATIBLE FLAME RETARDANTS FOR POLYMERIC COMPOSITIONS ALBEMARLE CORPORATION (US) 2025-11-26 EP claimed
CN-119855855-A Rheology modification of polymers with free radical initiators and thiourethanes 巴斯夫欧洲公司 2025-04-18 CN claimed
CN-119119809-A Coating for preparing mask, mask and preparation method of mask 浙江巨化新材料研究院有限公司 2024-12-13 CN claimed
CN-119039750-A High-foaming polylactic acid/poly (4-hydroxybutyrate) composite material and preparation method thereof 青岛科技大学 2024-11-29 CN claimed
US-12129404-B1 Methods of making adhesives containing post-consumer polymer RS INDUSTRIAL, INC. (US) 2024-10-29 US claimed
CN-118516058-A Adhesive film for packaging photovoltaic module and preparation method thereof 中能创低碳新能源科技(常州)有限责任公司 2024-08-20 CN claimed
CN-118480318-A Packaging adhesive film composition, packaging adhesive film and photovoltaic module 浙江福斯特新材料研究院有限公司 2024-08-13 CN claimed
WO-2024155758-A1 MODIFIED BROMINATED POLYSTYRENES AS COMPATIBLE FLAME RETARDANTS FOR POLYMERIC COMPOSITIONS ALBEMARLE CORPORATION (US) 2024-07-25 WO claimed
CN-118290321-A Method for preparing di (tert-butyl isopropyl peroxide) benzene by continuous method 山东阳谷华泰化工股份有限公司 2024-07-05 CN claimed
CN-118027266-A Comb-type oxazoline polylactic acid melt reinforcing agent 长沙学院 2024-05-14 CN claimed
US-6864323-B2 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSSA AG (DE) 2005-03-08 US claimed
US-20030114604-A1 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSA AG (DE) 2003-06-19 US claimed
US-6498200-B1 OXIRANE OR OXETANE RING COMPOUND, ORGANIC PEROXIDE, ONIUM SALT CATALYST, AND ALKALINE FILLER; CURES RAPIDLY; STABLE DOES NOT CAUSE INCREASE IN ELECTROCONDUCTIVITY OR CORROSION; SEALANT, BINDER, ENCAPSULATING AGENT, DIELECTRIC FILM NAMICS CORPORATION (JP) 2002-12-24 US claimed
US-20020077447-A1 Curable polyphenylene ether resin, composition made therefrom, and process for preparing the resin INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-06-20 US claimed
US-20020072585-A1 PPE derivatives and resin composition having the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2002-06-13 US claimed
US-6100335-A COMPRISING 10 TO 49% PROPYLENE POLYMER, 90 TO 51% ETHYLENE-VINYL ACETATE COPOLYMER IN WHICH THE VINYL ACETATE CONTENT IS FROM 12 TO 40% BY WEIGHT, ORGANIC PEROXIDE; AUTOMOBILE TRIMS SOLVAY (SOCIETE ANONYME) (BE) 2000-08-08 US claimed
EP-0911355-A2 Resorbable polyester Aesculap AG & Co. KG (DE) 1999-04-28 EP claimed
EP-0719828-B1 Compositions of propylene polymer and ethylene/vinyl acetate copolymer, process for their manufacture and sheets made thereof SOLVAY (BE) 1998-10-14 EP claimed
US-5658514-A MELTING WITH ADDITIVES: A NUCLEATING AGENT, FINE POWDER OF HIGH MELTING POLYMER, A PETROLEUM RESIN, A TERPENE RESIN AND AN ORGANIC PEROXIDE; COOLING; ROLLING; PRESSING IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-08-19 US claimed
US-5204037-A Adding at least one of a nucleating agent, powdered high melting powder, petroleum resin, terpene resin, organic peroxide and acrystalline propylene-based copolymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-04-20 US claimed