SCHEMBL449053

SCHEMBL449053

CC(COOC(C)(C)C)c1cc(C(C)COOC(C)(C)C)cc(C(C)COOC(C)(C)C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449071 0.88 RIPK1 (0.35)
SCHEMBL361156 0.87 RIPK1 (0.35)
SCHEMBL4074326 0.84 HDAC4 (0.37)
SCHEMBL1077953 0.82 RIPK1 (0.48)
SCHEMBL4084906 0.82 IDO1 (0.37)
SCHEMBL7933687 0.81 RIPK1 (0.31)
SCHEMBL4664725 0.79
SCHEMBL17710275 0.78 MAPK1 (0.49)
SCHEMBL28217326 0.77 RIPK1 (0.44)
SCHEMBL30801347 0.76 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227434-B2 Tin-free composition for crosslinking thermoplastic polyolefins EVONIK DEGUSSA GMBH (DE) 2019-03-12 US claimed
US-10030084-B2 Tin-free catalyst-containing composition for a Monosil process with optimized process properties EVONIK DEGUSSA GMBH (DE) 2018-07-24 US claimed
EP-3036281-B1 TIN-FREE COMPOSITION FOR CROSSLINKING THERMOPLASTIC POLYOLEFINES EVONIK DEGUSSA GMBH (DE) 2018-06-20 EP claimed
US-20160200852-A1 TIN-FREE COMPOSITION FOR CROSSLINKING THERMOPLASTIC POLYOLEFINS EVONIK DEGUSSA GMBH (DE) 2016-07-14 US claimed
US-20160200843-A1 TIN-FREE CATALYST-CONTAINING COMPOSITION FOR A MONOSIL PROCESS WITH OPTIMIZED PROCESS PROPERTIES EVONIK OPERATIONS GMBH (DE) 2016-07-14 US claimed
CN-103122077-A Silanol condensation catalysts for the cross-linking of filled and unfilled polymer compounds EVONIK DEGUSSA GMBH 2013-05-29 CN claimed
US-20110144278-A1 SILANOL CONDENSATION CATALYSTS FOR THE CROSS-LINKING OF FILLED AND UNFILLED POLYMER COMPOUNDS EVONIK DEGUSSA GMBH (DE) 2011-06-16 US claimed
EP-1288235-B1 Agents for the improvement of the vulcanisation behaviour in the preparation of grafted or crosslinked polymers and filled resins EVONIK DEGUSSA GMBH (DE) 2008-02-20 EP claimed
US-6864323-B2 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSSA AG (DE) 2005-03-08 US claimed
US-20030114604-A1 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSA AG (DE) 2003-06-19 US claimed
US-20240132681-A1 POLYETHYLENE COPOLYMERS AND TERPOLYMERS FOR TIE LAYERS AND METHODS THEREOF BRASKEM S.A. (BR) 2024-04-25 US disclosed
CN-112204090-B Bio-based EVA compositions, articles and methods thereof 布拉斯科有限公司 2024-03-15 CN disclosed
EP-3559107-B1 MODIFIED ETHYLENE VINYL ACETATE COMPOSITIONS, POLYMER BLENDS AND FILMS MADE THEREFROM BRASKEM SA (BR) 2023-12-13 EP disclosed
EP-4219131-A1 HIGH PERFORMANCE POLYOLEFIN FOR MATERIAL EXTRUSION Braskem America, Inc. (US) 2023-08-02 EP disclosed
US-11015035-B2 Foam composition with improved properties and applications thereof BRASKEM S.A. (BR) 2021-05-25 US disclosed
US-20030114604-A1 Composition for improving scorch conditions in the preparation of grafted and/or crosslinked polymers and of filled plastics DEGUSA AG (DE) 2003-06-19 US disclosed
US-5292791-A peroxide, hydroquinone derivative, and promoter ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-03-08 US disclosed
EP-0346863-B1 Mixture suited for the cross-linking of polymers, and process for the cross-linking of polymers with extended scorch time ATOCHEM ELF DEUTSCHLAND (DE) 1993-12-29 EP disclosed
US-5245084-A Peroxy compound, hydroquinone derivative, unsaturated compound LUPEROX GMBH (DE) 1993-09-14 US disclosed
EP-0346863-A1 Mixture suited for the cross-linking of polymers, and process for the cross-linking of polymers with extended scorch time Elf Atochem Deutschland GmbH (DE) 1989-12-20 EP disclosed