SCHEMBL449087

SCHEMBL449087

O=Cc1c(Nc2ccccc2)ccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
HPGD P15428 5/20 0.55
ATM Q13315 2/20 0.55
CYP3A4 P08684 2/20 0.55
HSD17B10 Q99714 2/20 0.55
CDC25B P30305 2/20 0.55
TP53 P04637 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
ERN1 O75460 1/20 0.51
MAPT P10636 7/20 0.46
KDM4E B2RXH2 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GAA P10253 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
RECQL P46063 2/20 0.46
GLA P06280 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337400 0.78 KMT2A (0.59) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL1617789 0.76 ALDH1A1 (0.64) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL30392844 0.76 ALDH1A1 (0.64) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL17022824 0.74 ALDH1A1 (0.62) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL8144519 0.73 ALDH1A1 (0.51) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL483213 0.73 ALDH1A1 (0.51) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL28532809 0.73 ERN1 (0.49) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL29483445 0.73 ALDH1A1 (0.51) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL4307897 0.73 HPGD (0.60) ALDH1A1HPGDATMCYP3A4HSD17B10
SCHEMBL28926952 0.73 ALDH1A1 (0.60) ALDH1A1HPGDATMCYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4715023-A1 HEAT TRANSFER FLUID ExxonMobil Technology and Engineering Company (US) 2026-03-25 EP disclosed
EP-4715960-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT Dr. Ing. h.c. F. Porsche Aktiengesellschaft (DE) 2026-03-25 EP disclosed
US-12358399-B2 Monitoring health of heat transfer fluids for electric systems ExxonMobil Technology and Engineering Company (US) 2025-07-15 US disclosed
US-20230166635-A1 MONITORING HEALTH OF HEAT TRANSFER FLUIDS FOR ELECTRIC SYSTEMS ExxonMobil Technology and Engineering Company (US) 2023-06-01 US disclosed
US-11629308-B2 Low viscosity gear oil compositions for electric and hybrid vehicles ExxonMobil Technology and Engineering Company (US) 2023-04-18 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-11092393-B1 Heat transfer fluids and methods of use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2021-08-17 US disclosed
US-20210040369-A1 Heat Transfer Fluids and Methods of Use EXXONMOBIL RES & ENG CO (US) 2021-02-11 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
US-20200277542-A1 LOW VISCOSITY GEAR OIL COMPOSITIONS FOR ELECTRIC AND HYBRID VEHICLES EXXONMOBIL RES & ENG CO (US) 2020-09-03 US disclosed
EP-2041050-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-04-01 EP disclosed
EP-2038386-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
US-20080207475-A1 High viscosity novel base stock lubricant viscosity blends HAIGH HEATHER M 2008-08-28 US disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
WO-1998037920-A1 MOVEMENT OF A TEST SUBSTANCE WITHIN A MEMBRANOUS SYSTEM UNIVERSITY OF MASSACHUSETTS (US) 1998-09-03 WO disclosed
US-5552067-A ADDITION OF PHOSPHATE TRIESTER AND TETRAHYDRONAPHTHALENE OR DECAHYDRONAPHTHALENE FMC CORPORATION (US) 1996-09-03 US disclosed