SCHEMBL483213

SCHEMBL483213

O=S(=O)(O)c1c(Nc2ccccc2)ccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
ATM Q13315 2/20 0.51
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
CDC25B P30305 1/20 0.51
HSD17B10 Q99714 1/20 0.51
SNCA P37840 3/20 0.51
TTR P02766 1/20 0.51
FABP4 P15090 1/20 0.51
CCNA2 P20248 1/20 0.51
CDK2 P24941 1/20 0.51
MAPK14 Q16539 1/20 0.51
CHAT P28329 1/20 0.51
NR4A1 P22736 1/20 0.50
MAPT P10636 5/20 0.48
KDM4E B2RXH2 3/20 0.48
GAA P10253 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483445 1.00 ALDH1A1 (0.51) ALDH1A1HPGDATMTP53CYP3A4
Ammonia Solution, Strong SCHEMBL9244903 0.98 NR4A1 (0.52) ALDH1A1HPGDATMTP53CYP3A4
Ammonia Solution, Strong SCHEMBL9244904 0.98 NR4A1 (0.52) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL7939417 0.92 SNCA (0.48) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL1140668 0.89 SNCA (0.43) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL5051397 0.88 SNCA (0.53) ALDH1A1CDC25BSNCATTRFABP4
Iodoacetamide SCHEMBL3286706 0.88 SNCA (0.42) ALDH1A1HPGDATMTP53CYP3A4
Questiomycin B SCHEMBL11673657 0.88 ALDH1A1 (0.45) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL28753723 0.84 KEAP1 (0.47) ALDH1A1HPGDATMTP53CYP3A4
SCHEMBL8144519 0.84 ALDH1A1 (0.51) ALDH1A1HPGDATMTP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019079222-A1 COMPOSITIONS FOR INHIBITING 3' REPAIR EXONUCLEASE 2 AND METHODS OF SCREENING FOR SUCH COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2019-04-25 WO claimed
US-7964363-B2 Direct determination of vitamin D in serum or plasma IMMUNDIAGNOSTIK AG (DE) 2011-06-21 US claimed
US-20110104781-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2011-05-05 US claimed
US-20100233782-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2010-09-16 US claimed
EP-2126586-B1 DIRECT DETERMINATION OF VITAMIN D IN SERUM OR PLASMA IMMUNDIAGNOSTIK AG (DE) 2010-06-30 EP claimed
US-7718353-B2 Proteins, sensors, and methods of characterizing analytes using the same UNIVERSITY OF MARYLAND BALTIMORE COUNTY (US) 2010-05-18 US claimed
US-20100068725-A1 DIRECT DETERMINATION OF VITAMIN D IN SERUM OR PLASMA IMMUNDIAGNOSTIK AG (DE) 2010-03-18 US claimed
US-20100034796-A1 Inhibitors of fatty acid oxidation for prophylaxis and treatment of diseases related to mitochondrial dysfunction MEDIGENE AG (DE) 2010-02-11 US claimed
EP-2126586-A1 DIRECT DETERMINATION OF VITAMIN D IN SERUM OR PLASMA Immundiagnostik AG (DE) 2009-12-02 EP claimed
EP-2118129-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2009-11-18 EP claimed
US-6872537-B1 Assays for the detection of microtubule depolymerization inhibitors REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-03-29 US claimed
WO-2004101769-A2 PROTEINS, SENSORS, AND METHODS OF CHARACTERIZING ANALYTES USING THE SAME UNIVERSITY OF MARYLAND BALTIMORE COUNTY (US) 2004-11-25 WO claimed
EP-1451585-A2 A NOVEL REAGENTLESS SENSING SYSTEM FOR MEASURING CARBOHYDRATES BASED ON THE GALACTOSE/GLUCOSE BINDING PROTEIN The University of Kentucky Research Foundation (US) 2004-09-01 EP claimed
US-6699969-B1 KIT CONTAINING MODULATE MICROTUBULE SEVERING PROTEINS; ACT AS POTENT ANTI-MITOTIC AGENTS; KATANIN; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-03-02 US claimed
US-20030232383-A1 Novel reagentless sensing system for measuring carbohydrates based on the galactose/glucose binding protein DAUNERT SYLVIA (US) 2003-12-18 US claimed
WO-2003060464-A2 A NOVEL REAGENTLESS SENSING SYSTEM FOR MEASURING CARBOHYDRATES BASED ON THE GALACTOSE/GLUCOSE BINDING PROTEIN UNIVERSITY OF KENTUCKY (US) 2003-07-24 WO claimed
US-5460944-A Conjugate of peroxidase and immunologically bindable substance organic buffer and aspartate salt BOEHRINGER MANNHEIM GMBH (DE) 1995-10-24 US claimed
EP-0415763-A2 Scanning tunneling microscope utilizing optical fluorescent for reading HOECHST CELANESE CORPORATION (US) 1991-03-06 EP claimed
EP-0000103-A1 Purification of glycoproteins and use of glycoproteins to form antiserum compositions AMERICAN HOME PRODUCTS CORPORATION (US) 1978-12-20 EP claimed
US-4049499-A Microbial medium having fluorescent growth indicator CORNING GLASS WORKS (US) 1977-09-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100034796-A1 Inhibitors of fatty acid oxidation for prophylaxis and treatment of diseases related to mitochondrial dysfunction CPT1A, CPT2, CPT1B ALDH1A1 289/4885HPGD 400/4885ATM 1878/4885
US-20030232383-A1 Novel reagentless sensing system for measuring carbohydrates based on the galactose/glucose binding protein LGALS3BP, GALE, MGAM ALDH1A1 4622/4885HPGD 4041/4885ATM 4598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.