Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 11/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491258 | 1.00 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1RAB9ANPC1LTB4R | |
| SCHEMBL4491265 | 1.00 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1RAB9ANPC1LTB4R | |
| SCHEMBL4515599 | 0.94 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1RAB9ANPC1LTB4R | |
| SCHEMBL4515586 | 0.94 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1RAB9ANPC1LTB4R | |
| SCHEMBL4515594 | 0.94 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1RAB9ANPC1LTB4R | |
| SCHEMBL13600901 | 0.92 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL4510714 | 0.88 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL4510711 | 0.88 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL4510706 | 0.88 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL13600998 | 0.86 | MAPT (0.50) | CYSLTR2CYSLTR1RAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | CYSLTR2 4/4885CYSLTR1 5/4885RAB9A 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.