Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492012 | 1.00 | MAP4K4 (0.55) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4477344 | 0.92 | ALDH1A1 (0.54) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4477340 | 0.92 | ALDH1A1 (0.54) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4479170 | 0.89 | ALDH1A1 (0.51) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4475317 | 0.89 | ALDH1A1 (0.52) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4475318 | 0.89 | ALDH1A1 (0.52) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4479172 | 0.89 | ALDH1A1 (0.51) | MAP4K4ALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL4477101 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL4477102 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 | |
| SCHEMBL1749521 | 0.78 | MCHR1 (0.54) | ALDH1A1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485647-B2 | 2-aminoquinoline derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20060287340-A1 | 2-Aminoquinoline derivatives | MSD K.K. (JP) | 2006-12-21 | — | — | US | disclosed |
| EP-1630162-A1 | 2-AMINOQUINOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287340-A1 | 2-Aminoquinoline derivatives | MCHR2, MC2R, MCHR1 | MAP4K4 1502/4885ALDH1A1 1932/4885HTR3E 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.