Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18049578 | 0.72 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL962966 | 0.70 | CTSD (1.00) | CTSDL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18056372 | 0.69 | MAPT (0.47) | CTSDL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL999490 | 0.69 | CTSD (0.61) | CTSDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL18038199 | 0.68 | MAPT (0.46) | CTSDL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28923861 | 0.68 | CTSD (0.56) | CTSDALDH1A1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL7539226 | 0.68 | CTSD (0.75) | CTSDL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11604066 | 0.68 | KMT2A (0.60) | CTSDL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL16377398 | 0.68 | POLB (0.68) | CTSDL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28237972 | 0.68 | MAPT (0.47) | ALDH1A1MAPTSMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094205-A2 | 3-ARYL-6-ARYL-7H-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2009-07-30 | — | — | WO | disclosed |