SCHEMBL449260

SCHEMBL449260

Fc1ncco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100765 0.67 HPGDS (0.46)
SCHEMBL16011600 0.63
SCHEMBL1159422 0.63
SCHEMBL29196122 0.63
SCHEMBL11130354 0.63 FAAH (0.39)
SCHEMBL25391442 0.62 CCR1 (0.32)
Hydrochloric Acid SCHEMBL3063616 0.62
SCHEMBL317377 0.62
SCHEMBL4300474 0.62
SCHEMBL323900 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105308040-A 1, 3-diaminocyclopentanecarboxamide derivatives MERCK PATENT GMBH 2016-02-03 CN claimed
CN-104193693-A NOVEL HERBICIDES SYNGENTA LTD 2014-12-10 CN claimed
US-20240109842-A1 ACRYLAMIDE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-04-04 US disclosed
US-11905258-B2 2-aminoaryl-5-aryloxazole analogs for the treatment of neurodegenerative diseases SOUTHERN RESEARCH INSTITUTE (US) 2024-02-20 US disclosed
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
US-20230002331-A1 2-AMINOARYL-5-ARYLOXAZOLE ANALOGS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SOUTHERN RES INST (US) 2023-01-05 US disclosed
CN-115530185-A Composition containing oxazole fluoride amide and preparation method and application thereof 安徽省四达农药化工有限公司 2022-12-30 CN disclosed
CN-115530185-A Composition containing oxazole fluoride amide and preparation method and application thereof 安徽省四达农药化工有限公司 2022-12-30 CN disclosed
US-20210188791-A1 2-AMINOARYL-5-ARYLOXAZOLE ANALOGS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SOUTHERN RESEARCH INSTITUTE 2021-06-24 US disclosed
WO-2021117733-A1 ACRYLAMIDE COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-06-17 WO disclosed
CN-111165503-A Pesticide composition containing fluxapyroxad and rotenone 浙江中山化工集团股份有限公司 2020-05-19 CN disclosed
EP-2375898-B1 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-09-16 EP disclosed
CN-104193693-A NOVEL HERBICIDES SYNGENTA LTD 2014-12-10 CN disclosed
US-8889595-B2 Herbicides SYNGENTA PARTICIPATIONS AG (CH) 2014-11-18 US disclosed
US-20120065064-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-03-15 US disclosed
CN-102300458-A New herbicides 2011-12-28 CN disclosed
US-20080125409-A1 1,5-Diheterocycle-1H-Triazole Derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2008-05-29 US disclosed
US-20080064682-A1 Pyrazole Derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2008-03-13 US disclosed
EP-1803719-A1 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-07-04 EP disclosed
EP-1762568-A1 PYRAZOLE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-03-14 EP disclosed