Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451418 | 0.89 | EP300 (0.44) | GRIK1EP300 | |
| SCHEMBL445701 | 0.87 | EP300 (0.52) | EP300 | |
| SCHEMBL10600503 | 0.85 | EP300 (0.55) | EP300 | |
| SCHEMBL451987 | 0.85 | EP300 (0.55) | EP300 | |
| SCHEMBL10503949 | 0.83 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL447238 | 0.83 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL10505273 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL10751353 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL10504070 | 0.79 | FAAH (0.39) | — | |
| SCHEMBL10746558 | 0.79 | FAAH (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-8883928-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | disclosed |
| US-20120065331-A1 | SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS | ALCON INC. (CH) | 2012-03-15 | — | — | US | disclosed |
| US-8079703-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2011-12-20 | — | — | US | disclosed |
| EP-2307190-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011493-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100014047-A1 | Silicone-Containing Polymeric Materials with Hydrolyzable Groups | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| US-7279096-B2 | Polymer based permeable membrane for removal of ions | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-10-09 | — | — | US | disclosed |
| US-20060047098-A1 | Recyclable crosslinked polymers with saturated main chain and thermally reversible urethane crosslink points | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 2006-03-02 | — | — | US | disclosed |
| EP-1572784-A1 | RECYCLABLE CROSSLINKED POLYMERS WITH SATURATED MAIN CHAIN AND THERMALLY REVERSIBLE URETHANE CROSSLINK POINTS | The Furukawa Electric Co., Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
| US-20050019302-A1 | Polymer based permeable membrane for removal of ions | MURRAY GEORGE M (US) | 2005-01-27 | — | — | US | disclosed |
| US-6780323-B2 | Polymer based permeable membrane for removal of ions | THE JOHNS HOPKINS UNIVERSITY | 2004-08-24 | — | — | US | disclosed |
| WO-2004037901-A1 | RECYCLABLE CROSSLINKED POLYMERS WITH SATURATED MAIN CHAIN AND THERMALLY REVERSIBLE URETHANE CROSSLINK POINTS | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 2004-05-06 | — | — | WO | disclosed |
| US-20030113234-A1 | Polymer based permeable membrane for removal of ions | JOHNS HOPKINS UNIVERSITY, THE | 2003-06-19 | — | — | US | disclosed |
| WO-2003033575-A1 | POLYMER BASED PERMEABLE MEMBRANE FOR REMOVAL OF IONS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-04-24 | — | — | WO | disclosed |
| EP-0444508-B1 | Ethylenically unsaturated fluorine-containing urethan derivatives and process for their preparation | HOECHST AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| EP-0444508-A2 | Ethylenically unsaturated fluorine-containing urethan derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0141295-B1 | UNSATURATED ESTER ISOCYANATES, PROCESS FOR THEIR PREPARATION AND THEIR UTILIZATION IN THE PRODUCTION OF OLEFINICALLY UNSATURATED OLIGOURETHANES | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |