Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600805 | 0.85 | HTT (0.44) | HTTPOLBPTGS1PTGS2KDM4E | |
| SCHEMBL2910532 | 0.78 | POLB (0.62) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL4040603 | 0.77 | NPC1 (0.50) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL4040605 | 0.77 | NPC1 (0.50) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL5561790 | 0.77 | PTPN1 (0.56) | PTGS1PTPN1 | |
| SCHEMBL5563077 | 0.77 | PTPN1 (0.56) | PTGS1PTPN1 | |
| SCHEMBL7096822 | 0.77 | HTT (0.45) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL8600788 | 0.76 | HTT (0.47) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL9053303 | 0.76 | HTT (0.44) | HTTPOLBKDM4ETP53GAA | |
| SCHEMBL9015990 | 0.76 | HTT (0.44) | HTTPOLBPTGS2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622591-B2 | Route to α- tocopheryl alkanoates and percursors thereof | DSM IP ASSETS B.V. (NL) | 2009-11-24 | — | — | US | disclosed |
| US-20070032667-A1 | Route to alpha-tocopheryl alkanoates and percursors thereof | DSM IP ASSETS B.V. (NL) | 2007-02-08 | — | — | US | disclosed |
| EP-1663937-A2 | SYNTHESIS OF ALPHA-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF | DSM IP Assets B.V. (NL) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026142-A2 | SYNTHESIS OF ALPHA-TOCOPHERYL ALKANOATES AND PRECURSORS THEREOF | DSM IP ASSETS B.V. (NL) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032667-A1 | Route to alpha-tocopheryl alkanoates and percursors thereof | TTPA, VKORC1L1, VKORC1 | HTT 3912/4885POLB 2039/4885PTGS1 282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.