Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | VDR | P11473 | 9/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395394 | 0.93 | HDAC6 (0.51) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3389749 | 0.85 | HDAC3 (0.51) | HDAC6HDAC3VDRAR | |
| SCHEMBL3392848 | 0.83 | HDAC6 (0.51) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3390977 | 0.82 | HDAC6 (0.49) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3391080 | 0.81 | HDAC3 (0.45) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3392175 | 0.80 | HDAC6 (0.48) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3394911 | 0.79 | HDAC6 (0.46) | HDAC6HDAC3VDRHDAC1AR | |
| Acetic Acid Methyl Ester SCHEMBL3392963 | 0.79 | HDAC6 (0.46) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3395595 | 0.79 | HDAC3 (0.45) | HDAC6HDAC3VDRHDAC1AR | |
| SCHEMBL3392960 | 0.79 | HDAC6 (0.44) | HDAC6HDAC3VDRHDAC1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601850-B2 | less hypercalcemic than 1a,25 dihydroxy vitamin D3; bone disorders, psoriasis | ELI LILLY AND COMPANY (US) | 2009-10-13 | — | — | US | disclosed |
| US-20060287536-A1 | Phenyl-thiophene type vitamin d receptor modulators | ELI LILLY AND COMPANY | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287536-A1 | Phenyl-thiophene type vitamin d receptor modulators | VDR, CYP2R1, CYP24A1 | HDAC6 4626/4885HDAC3 2229/4885VDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.