Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.47 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818397 | 0.85 | SRC (0.46) | SRCCASP1CASP8 | |
| SCHEMBL4489025 | 0.84 | SRC (0.58) | SRCCASP1CASP8 | |
| SCHEMBL4501161 | 0.84 | SRC (0.49) | SRCCASP1CASP8 | |
| SCHEMBL4484988 | 0.80 | SRC (0.55) | SRCCASP1CASP8 | |
| SCHEMBL5217351 | 0.79 | SRC (0.48) | SRCCASP1CASP8 | |
| SCHEMBL5216219 | 0.78 | L3MBTL1 (0.34) | SRC | |
| Hydrochloric Acid SCHEMBL4497350 | 0.77 | L3MBTL1 (0.33) | SRC | |
| SCHEMBL4488508 | 0.75 | SRC (0.54) | SRC | |
| SCHEMBL5455919 | 0.75 | SRC (0.34) | SRC | |
| SCHEMBL4486664 | 0.75 | METAP1 (0.45) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550453-B2 | Anticancer agents; colon cancer or hepatocellular carcinoma; analogs of bengamide where the caprolactam ring is changed and/or substituted e.g. N-(2-Methyl-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepin-4-yl)-(E)-(2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8,8-dimethylnon-6-enamide | AVENTIS PHARMA SA (FR) | 2009-06-23 | — | — | US | disclosed |
| EP-1819679-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | Aventis Pharma S.A. (FR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056696-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-06-01 | — | — | WO | disclosed |