Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501161 | 0.85 | SRC (0.49) | SRCSIGMAR1CASP1CASP8 | |
| SCHEMBL13818391 | 0.85 | SRC (0.47) | SRCALDH1A1CASP1 | |
| SCHEMBL4489025 | 0.83 | SRC (0.58) | SRCCASP1CASP8 | |
| SCHEMBL4484988 | 0.83 | SRC (0.55) | SRCSIGMAR1CASP1CASP8 | |
| SCHEMBL5310594 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4494868 | 0.79 | SRC (0.47) | SRCCASP1CASP8 | |
| Hydrochloric Acid SCHEMBL4494597 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4488508 | 0.77 | SRC (0.54) | SRCALDH1A1 | |
| SCHEMBL5449462 | 0.76 | ALDH1A1 (0.37) | SRCSIGMAR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4498022 | 0.75 | METAP1 (0.46) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819679-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | Aventis Pharma S.A. (FR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056696-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-06-01 | — | — | WO | disclosed |