Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.53 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 5/20 | 0.43 |
| ▸ | F3 | P13726 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818420 | 0.84 | SRC (0.46) | ACEMMEXIAPF7F3 | |
| SCHEMBL3156878 | 0.83 | XIAP (0.62) | ACEMMEXIAPF7F3 | |
| SCHEMBL3156873 | 0.83 | XIAP (0.62) | ACEMMEXIAPF7F3 | |
| SCHEMBL3157917 | 0.78 | XIAP (0.56) | ACEMMEXIAPF7F3 | |
| SCHEMBL3157911 | 0.78 | XIAP (0.56) | ACEMMEXIAPF7F3 | |
| SCHEMBL13818426 | 0.78 | F2 (0.43) | ACEMMEF7F3F2 | |
| SCHEMBL3148741 | 0.78 | RIPK1 (0.60) | ACEMMEXIAPF7F3 | |
| SCHEMBL3148748 | 0.78 | RIPK1 (0.60) | ACEMMEXIAPF7F3 | |
| SCHEMBL3914724 | 0.77 | MME (0.53) | ACEMMEXIAPRIPK1 | |
| Hydrochloric Acid SCHEMBL4485518 | 0.77 | MEN1 (0.43) | ACEMMEF7F3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550453-B2 | Anticancer agents; colon cancer or hepatocellular carcinoma; analogs of bengamide where the caprolactam ring is changed and/or substituted e.g. N-(2-Methyl-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepin-4-yl)-(E)-(2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8,8-dimethylnon-6-enamide | AVENTIS PHARMA SA (FR) | 2009-06-23 | — | — | US | disclosed |
| US-20070244087-A1 | 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2007-10-18 | — | — | US | disclosed |
| EP-1819679-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | Aventis Pharma S.A. (FR) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056696-A2 | 2-ALCOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244087-A1 | 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | HCCS, ALKBH2, ALKBH3 | ACE 3724/4885MME 3840/4885XIAP 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.