⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829234 | 0.69 | CYP11B2 (0.31) | — | |
| SCHEMBL20554474 | 0.68 | — | — | |
| SCHEMBL2180063 | 0.65 | — | — | |
| SCHEMBL2176290 | 0.64 | — | — | |
| SCHEMBL20554220 | 0.64 | — | — | |
| SCHEMBL328741 | 0.62 | — | — | |
| SCHEMBL445880 | 0.62 | — | — | |
| SCHEMBL449784 | 0.62 | — | — | |
| SCHEMBL4927342 | 0.60 | — | — | |
| SCHEMBL4917687 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036291-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2024-07-16 | — | — | US | claimed |
| CN-118005611-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-20210379211-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2021-12-09 | — | — | US | claimed |
| EP-3186241-B1 | PROBES FOR IMAGING HUNTINGTON PROTEIN | CHDI FOUNDATION INC (US) | 2020-10-07 | — | — | EP | claimed |
| US-20170281804-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | EVOTEC (UK) LTD. (GB) | 2017-10-05 | — | — | US | claimed |
| EP-3186241-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2017-07-05 | — | — | EP | claimed |
| WO-2016033436-A1 | PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. (US) | 2016-03-03 | — | — | WO | claimed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | claimed |
| US-20140128373-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2014-05-08 | — | — | US | claimed |
| CN-103517710-A | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC | 2014-01-15 | — | — | CN | claimed |
| EP-2672967-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2013-12-18 | — | — | EP | claimed |
| WO-2013055910-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-04-18 | — | — | WO | claimed |
| WO-2012109075-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2012-08-16 | — | — | WO | claimed |
| US-12036291-B2 | Probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| CN-118005611-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-107074817-B | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-5334748-A | A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-08-02 | — | — | US | disclosed |
| US-5198444-A | Methyl α-(2-substituted)pyrid-3-yl-β-methoxyacrylates, compositions containing them and their use as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | disclosed |
| US-5158954-A | For agriculture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-27 | — | — | US | disclosed |
| US-5008276-A | Plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-16 | — | — | US | disclosed |