SCHEMBL4495707

SCHEMBL4495707

CC(N)Cc1ccc(CO)cc1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.68
SLC6A2 P23975 5/20 0.68
SLC6A3 Q01959 3/20 0.61
SLC6A4 P31645 4/20 0.60
MAOA P21397 2/20 0.60
SIGMAR1 Q99720 1/20 0.60
CYP2A6 P11509 1/20 0.60
ADORA2A P29274 1/20 0.60
ADORA1 P30542 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513202 1.00 TAAR1 (0.68) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872752 0.87 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872755 0.87 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL9651928 0.82 TAAR1 (0.63) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydroxyamphetamine SCHEMBL125442 0.81 TAAR1 (1.00) TAAR1SLC6A2SLC6A3SLC6A4MAOA
(S)-P-Hydroxyamphetamine SCHEMBL256809 0.81 TAAR1 (1.00) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydroxyamphetamine SCHEMBL125440 0.81 TAAR1 (1.00) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL2141223 0.80 PNMT (0.60) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL5259036 0.80 PNMT (0.60) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL2141228 0.80 PNMT (0.60) TAAR1SLC6A2SLC6A3SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115948936-B Extraction paper, preparation method thereof and application of extraction paper in amphetamine drugs detection 中科检测技术服务(广州)股份有限公司 2024-01-26 CN claimed
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
CN-118443818-A Silanized polydopamine modified membrane, preparation method thereof and application thereof in amphetamine drugs and metabolite detection 华南理工大学 2024-08-06 CN disclosed
CN-115948936-B Extraction paper, preparation method thereof and application of extraction paper in amphetamine drugs detection 中科检测技术服务(广州)股份有限公司 2024-01-26 CN disclosed
CN-115948936-A Extraction paper, preparation method thereof and application of extraction paper in detection of amphetamine drugs 中科检测技术服务(广州)股份有限公司 2023-04-11 CN disclosed
CN-115855906-A Method for detecting amphetamine in drugs based on anthracene-based probe 中国科学院新疆理化技术研究所 2023-03-28 CN disclosed
US-10000555-B2 Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus SEATTLE GENETICS, INC. (US) 2018-06-19 US disclosed
US-20130123465-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS SEATTLE GENETICS, INC. (US) 2013-05-16 US disclosed
US-8343928-B2 Monomethylvaline compounds having phenylalanine side-chain replacements at the C-terminus SEATTLE GENETICS, INC. (US) 2013-01-01 US disclosed
CN-202471713-U Methyl-amphetamine reagent strip HANGZHOU CLONGENE BIOTECH CO LTD 2012-10-03 CN disclosed
US-20050187223-A1 Substituted heterocyclic compounds and methods of use AMGEN, INC. 2005-08-25 US disclosed
WO-2005070932-A2 SUBSTITUTED HETEROCYCLIC COMPOUNDS AND METHODS OF USE AMGEN INC. (US) 2005-08-04 WO disclosed
US-5086181-A Promoter for animal feeds; animal growth regulators BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
US-4988694-A Promoters for animal growth regulators for animal feeds BAYER AKTIENGESELLSCHAFT (DE) 1991-01-29 US disclosed
US-4960783-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0339345-A2 4-Bromo-6-chloro-5-amino-2-pyridyl-ethanol amines, process for their preparation and their use as performance stimulators BAYER AG (DE) 1989-11-02 EP disclosed
EP-0325802-A1 Use of benzimidazole derivatives as operating capacity promotors BAYER AG (DE) 1989-08-02 EP disclosed
EP-0325131-A2 Pyrimidine derivatives as performance stimulating agents BAYER AG (DE) 1989-07-26 EP disclosed
US-4845262-A NITRILE CONTAINING BAYER AKTIENGESELLSCHAFT (DE) 1989-07-04 US disclosed
EP-0259750-A2 Aryl ethanol amines, process for their preparation and their use as growth promotors BAYER AG (DE) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130123465-A1 MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS MMAB, PTMS, DNPEP TAAR1 4174/4885SLC6A2 3436/4885SLC6A3 3411/4885
US-20050187223-A1 Substituted heterocyclic compounds and methods of use MYLK2, MUSK, MAPT TAAR1 2835/4885SLC6A2 2558/4885SLC6A3 3180/4885
US-10000555-B2 Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus PTMS, MMAB, DNPEP TAAR1 4189/4885SLC6A2 3422/4885SLC6A3 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.