Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.37 |
| ▸ | LDHB | P07195 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480914 | 0.80 | LDHA (0.33) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL22418970 | 0.71 | LDHA (0.47) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL31586352 | 0.71 | LDHA (0.47) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL5441713 | 0.67 | LDHA (0.44) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL29504076 | 0.67 | LDHA (0.44) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL3585516 | 0.65 | LDHA (0.33) | LDHALDHBALB | |
| SCHEMBL21757301 | 0.62 | TYMP (0.34) | — | |
| SCHEMBL25451187 | 0.62 | LDHA (0.44) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL2012332 | 0.62 | LDHA (0.40) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL18009661 | 0.62 | LDHA (0.48) | LDHALDHBFABP3FABP4ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |