Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 5/20 | 0.40 |
| ▸ | LDHB | P07195 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | EIF4A3 | P38919 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926429 | 0.93 | SMN1; SMN2 (0.42) | LDHALDHBSMN1; SMN2PKMFABP3 | |
| SCHEMBL7855511 | 0.93 | SMN1; SMN2 (0.42) | LDHALDHBSMN1; SMN2PKMFABP3 | |
| SCHEMBL8357047 | 0.86 | SMN1; SMN2 (0.41) | LDHALDHBSMN1; SMN2PKMFABP3 | |
| SCHEMBL12650279 | 0.86 | LDHA (0.40) | LDHALDHBSMN1; SMN2PKMFABP3 | |
| SCHEMBL31586352 | 0.82 | LDHA (0.47) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL12631960 | 0.79 | PKM (0.34) | SMN1; SMN2PKM | |
| SCHEMBL12695313 | 0.77 | PKM (0.37) | SMN1; SMN2PKMTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29504076 | 0.77 | LDHA (0.44) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL5441713 | 0.77 | LDHA (0.44) | LDHALDHBFABP3FABP4ALB | |
| SCHEMBL22418970 | 0.76 | LDHA (0.47) | LDHALDHBFABP3FABP4ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745252-B2 | Cross-linking moiety | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-08-29 | — | — | US | disclosed |
| US-9745252-B2 | Cross-linking moiety | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-08-29 | — | — | US | disclosed |
| US-9745252-B2 | Cross-linking moiety | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-08-29 | — | — | US | disclosed |
| EP-2507309-A1 | A CROSS-LINKING MOIETY | National University of Singapore (SG) | 2012-10-10 | — | — | EP | disclosed |
| US-20120244294-A1 | CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-09-27 | — | — | US | disclosed |
| US-20120244294-A1 | CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-09-27 | — | — | US | disclosed |
| US-20120244294-A1 | CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2012-09-27 | — | — | US | disclosed |
| WO-2011068482-A1 | A CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-06-09 | — | — | WO | disclosed |
| WO-2011068482-A1 | A CROSS-LINKING MOIETY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2011-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244294-A1 | CROSS-LINKING MOIETY | ARF1, ARF6, ARF4 | LDHA 4840/4885LDHB 4809/4885SMN1; SMN2 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.