SCHEMBL449598

SCHEMBL449598

CCCCCCCCCCCCCCCC/C=C/[O]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.61
TRPV1 Q8NER1 1/20 0.61
FABP3 P05413 5/20 0.56
TSHR P16473 1/20 0.55
TERT O14746 2/20 0.52
GMNN O75496 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
APEX1 P27695 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HSD17B10 Q99714 1/20 0.52
DUSP3 P51452 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449542 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL129255 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL131677 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL451503 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL450161 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL131304 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL130541 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL449541 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL450162 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL130013 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1551370-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2005-07-13 EP claimed
WO-2004032900-A1 AGGREGATE WITH INCREASED DEFORMABILITY, COMPRISING AT LEAST THREE AMPHIPATS, FOR IMPROVED TRANSPORT THROUGH SEMI-PERMEABLE BARRIERS AND FOR THE NON-INVASIVE DRUG APPLICATION IN VIVO, ESPECIALLY THROUGH THE SKIN IDEA AG (DE) 2004-04-22 WO claimed
EP-0014815-A2 Peptide derivatives, process for their preparation and intermediates, and pharmaceutical compositions containing one of these compounds CIBA-GEIGY AG (CH) 1980-09-03 EP claimed
CN-112180079-B Stable liposome particle and application thereof in immune turbidimetry detection 上海睿康生物科技有限公司 2024-04-19 CN disclosed
CN-116745272-A Compound, cell vesicle staining agent, and method for fluorescent staining of cell vesicles 国立大学法人东海国立大学机构 2023-09-12 CN disclosed
EP-2883865-B1 Compound capable of binding S1P receptor and pharmaceutical use thereof ONO PHARMACEUTICAL CO (JP) 2019-09-25 EP disclosed
EP-2939659-B1 HAIR CLEANSING COMPOSITION KAO CORP (JP) 2018-05-30 EP disclosed
EP-2939658-B1 GEL HAIR COSMETIC KAO CORP (JP) 2018-01-31 EP disclosed
US-9849075-B2 Gel hair cosmetic KAO CORPORATION (JP) 2017-12-26 US disclosed
US-9566217-B2 Hair cleansing composition KAO CORPORATION (JP) 2017-02-14 US disclosed
EP-2740724-B1 COMPOUND FOR TREATING CARTILAGE DISORDERS ONO PHARMACEUTICAL CO (JP) 2016-12-28 EP disclosed
EP-0071892-B1 PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-10-23 EP disclosed
US-4439425-A IMMUNOLOGY CIBA-GEIGY CORPORATION (US) 1984-03-27 US disclosed
US-4410689-A MASKED ISOCYANATES THE UPJOHN COMPANY (US) 1983-10-18 US disclosed
EP-0088046-A2 Lipids in the aqueous phase CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed
EP-0071892-A2 Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP disclosed
US-4354034-A Dihalophenoxypropionic acids and their derivatives, and their use as cotton desiccants IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-10-12 US disclosed
US-4349663-A Bis(cyclic ureas) monomer compositions useful in making polyurethane polymers THE UPJOHN COMPANY (US) 1982-09-14 US disclosed
US-4257801-A Cotton desiccation with phenoxyalkanoic acids IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-03-24 US disclosed
EP-0014815-A2 Peptide derivatives, process for their preparation and intermediates, and pharmaceutical compositions containing one of these compounds CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed