SCHEMBL449542

SCHEMBL449542

CCCCCCCCCCCCCCCCCC=C[O]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.61
TRPV1 Q8NER1 1/20 0.61
FABP3 P05413 5/20 0.56
TSHR P16473 1/20 0.55
TERT O14746 2/20 0.52
GMNN O75496 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
APEX1 P27695 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HSD17B10 Q99714 1/20 0.52
DUSP3 P51452 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129255 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL131677 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL451503 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL450161 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL131304 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL130541 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL449541 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL450162 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL449598 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT
SCHEMBL130013 1.00 FAAH (0.61) FAAHTRPV1FABP3TSHRTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2883865-B1 Compound capable of binding S1P receptor and pharmaceutical use thereof ONO PHARMACEUTICAL CO (JP) 2019-09-25 EP disclosed
EP-2939659-B1 HAIR CLEANSING COMPOSITION KAO CORP (JP) 2018-05-30 EP disclosed
EP-2939658-B1 GEL HAIR COSMETIC KAO CORP (JP) 2018-01-31 EP disclosed
US-9849075-B2 Gel hair cosmetic KAO CORPORATION (JP) 2017-12-26 US disclosed
US-9566217-B2 Hair cleansing composition KAO CORPORATION (JP) 2017-02-14 US disclosed
EP-2740724-B1 COMPOUND FOR TREATING CARTILAGE DISORDERS ONO PHARMACEUTICAL CO (JP) 2016-12-28 EP disclosed
US-20160000690-A1 GEL HAIR COSMETIC KAO CORPORATION (JP) 2016-01-07 US disclosed
US-20150352029-A1 HAIR CLEANSING COMPOSITION KAO CORPORATION (JP) 2015-12-10 US disclosed
CN-102365277-B JUN N-terminal kinase inhibitors ELAN PHARMACEUTICALS, INC. (US) 2015-11-25 CN disclosed
EP-2939658-A1 GEL HAIR COSMETIC Kao Corporation (JP) 2015-11-04 EP disclosed
EP-0627406-A1 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-12-07 EP disclosed
EP-0619345-A1 Phthalocyanine compound and optical recording medium containing it MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-10-12 EP disclosed
CN-1090272-A Novel substituted azetidinones as anti-inflammatory and anti-allergic agents MERCK & CO INC (US) 1994-08-03 CN disclosed
CN-1059517-A Acetamide derivative ICI PLC (GB) 1992-03-18 CN disclosed
EP-0088046-B1 LIPIDS IN THE AQUEOUS PHASE CIBA-GEIGY AG (CH) 1987-12-09 EP disclosed
US-4619794-A Spontaneous preparation of small unilamellar liposomes CIBA-GEIGY CORPORATION (US) 1986-10-28 US disclosed
EP-0071892-B1 PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-10-23 EP disclosed
US-4410689-A MASKED ISOCYANATES THE UPJOHN COMPANY (US) 1983-10-18 US disclosed
EP-0088046-A2 Lipids in the aqueous phase CIBA-GEIGY AG (CH) 1983-09-07 EP disclosed
US-4349663-A Bis(cyclic ureas) monomer compositions useful in making polyurethane polymers THE UPJOHN COMPANY (US) 1982-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000690-A1 GEL HAIR COSMETIC H1-0, POLR1C, H1-10 FAAH 274/4885TRPV1 775/4885FABP3 3940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.