Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 6/20 | 0.45 |
| ▸ | KDR | P35968 | 6/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | LHCGR | P22888 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 3/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498597 | 0.86 | EPHA2 (0.42) | EPHA2KDREPHB4RXRBCCR3 | |
| SCHEMBL4505587 | 0.81 | EPHA2 (0.47) | EPHA2KDREPHB4CCR3 | |
| SCHEMBL4504899 | 0.78 | EPHA2 (0.45) | EPHA2KDREPHB4CCR3 | |
| SCHEMBL4505511 | 0.78 | DRD4 (0.43) | EPHA2KDREPHB4CCR3 | |
| Trifluoroacetic Acid SCHEMBL4499863 | 0.78 | SMN1; SMN2 (0.44) | EPHA2KDREPHB4CCR3NPC1 | |
| SCHEMBL4505525 | 0.77 | EPHA2 (0.45) | EPHA2KDREPHB4CCR3 | |
| Hydrochloric Acid SCHEMBL4513041 | 0.77 | DRD4 (0.44) | EPHA2KDREPHB4CCR3NPC1 | |
| SCHEMBL4498562 | 0.77 | EPHA2 (0.44) | EPHA2KDREPHB4CCR3 | |
| SCHEMBL4516917 | 0.77 | EPHA2 (0.44) | EPHA2KDREPHB4 | |
| SCHEMBL4511583 | 0.76 | EPHA2 (0.44) | EPHA2KDREPHB4CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | EPHA2 4379/4885KDR 618/4885EPHB4 2932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.