Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 13/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | STAT3 | P40763 | 2/20 | 0.71 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757524 | 0.82 | PTGER1 (0.67) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL759700 | 0.80 | PTGER1 (0.78) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL757179 | 0.80 | PTGER1 (0.75) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL18762166 | 0.76 | PTGER1 (0.78) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL704436 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL7875050 | 0.76 | PTGER1 (0.62) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| SCHEMBL4505850 | 0.75 | SMN1; SMN2 (0.67) | SMN1; SMN2NPSR1HPGDHTTALDH1A1 | |
| SCHEMBL758338 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1HPGDHTTCYP1A2 | |
| Trifluoroacetic Acid SCHEMBL4516452 | 0.74 | SMN1; SMN2 (0.63) | SMN1; SMN2NPSR1HPGDHTTALDH1A1 | |
| SCHEMBL4509901 | 0.74 | SMN1; SMN2 (0.66) | SMN1; SMN2NPSR1HPGDCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SMN1; SMN2 2075/4885NPSR1 3559/4885HPGD 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.