Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 3/20 | 0.38 |
| ▸ | GIPR | P48546 | 1/20 | 0.38 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | BCR | P11274 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516945 | 0.89 | HSD17B13 (0.42) | HSD17B13PPARAPPARGHDAC1HDAC6 | |
| SCHEMBL4505012 | 0.84 | HDAC1 (0.44) | PPARDPPARAPPARGHDAC1HDAC6 | |
| SCHEMBL4372432 | 0.74 | HSD17B13 (0.43) | HSD17B13HDAC1HDAC6PDE2AP2RX7 | |
| SCHEMBL3235731 | 0.69 | AKR1C2 (0.43) | HSD17B13AKR1C2AKR1C1GCGRABL1 | |
| SCHEMBL3318427 | 0.68 | TSHR (0.45) | SCN5APPARDPPARAMBOAT4HTR2C | |
| SCHEMBL3319310 | 0.67 | TSHR (0.42) | SCN5APPARDPPARAPPARGMBOAT4 | |
| SCHEMBL1491072 | 0.67 | KDM4E (0.58) | SCN5APPARDPPARAPPARGMBOAT4 | |
| SCHEMBL3604297 | 0.66 | ALDH1A1 (0.46) | SCN5APPARDPPARAPPARGHTR2C | |
| SCHEMBL3318423 | 0.66 | TSHR (0.43) | SCN5APPARDPPARAMBOAT4HTR2C | |
| SCHEMBL3316523 | 0.65 | MBOAT4 (0.43) | SCN5APPARDPPARAMBOAT4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318429-A1 | Compounds, Compositions and Methods Comprising Heteroaromatic Derivatives | CFTR, PKD1, PKD2 | HSD17B13 924/4885AKR1C2 396/4885AKR1C1 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.