Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953256 | 1.00 | PPARD (0.42) | PPARDFFAR1PPARATBXA2RPTGDR | |
| SCHEMBL27669751 | 0.85 | ADRA2A (0.36) | PPARDFFAR1 | |
| SCHEMBL27669752 | 0.85 | ADRA2A (0.36) | PPARDFFAR1 | |
| SCHEMBL4493978 | 0.82 | ADRA2A (0.47) | PPARDFFAR1PPARA | |
| SCHEMBL3952620 | 0.82 | ADRA2A (0.47) | PPARDFFAR1PPARA | |
| SCHEMBL4506871 | 0.81 | PPARD (0.43) | PPARDFFAR1PPARA | |
| SCHEMBL3957552 | 0.81 | PPARD (0.43) | PPARDFFAR1PPARA | |
| SCHEMBL4497378 | 0.79 | PPARD (0.51) | PPARDFFAR1PPARA | |
| SCHEMBL3957347 | 0.79 | PPARD (0.51) | PPARDFFAR1PPARA | |
| SCHEMBL3957195 | 0.79 | PPARD (0.46) | PPARDFFAR1PPARATBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605171-B2 | (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists | MERCK & CO., INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | MERCK & CO., INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | S1PR1, S1PR3, S1PR5 | PPARD 802/4885FFAR1 44/4885PPARA 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.