Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957347 | 1.00 | PPARD (0.51) | PPARDKDM4CKDM6BPPARAFFAR1 | |
| SCHEMBL27669768 | 0.88 | KDM4C (0.47) | PPARDKDM4CKDM6BMTNR1AMTNR1B | |
| SCHEMBL27669766 | 0.88 | KDM4C (0.47) | PPARDKDM4CKDM6BMTNR1AMTNR1B | |
| SCHEMBL4496501 | 0.81 | DRD2 (0.45) | PPARDPPARA | |
| SCHEMBL3949854 | 0.81 | DRD2 (0.45) | PPARDPPARA | |
| SCHEMBL4493978 | 0.81 | ADRA2A (0.47) | PPARDPPARAFFAR1 | |
| SCHEMBL3952620 | 0.81 | ADRA2A (0.47) | PPARDPPARAFFAR1 | |
| SCHEMBL4506871 | 0.80 | PPARD (0.43) | PPARDKDM4CKDM6BPPARAFFAR1 | |
| SCHEMBL3957552 | 0.80 | PPARD (0.43) | PPARDKDM4CKDM6BPPARAFFAR1 | |
| SCHEMBL4496981 | 0.79 | PPARD (0.42) | PPARDPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605171-B2 | (3,4-disubstituted)propanoic carboxylates as S1P (Edg) receptor agonists | MERCK & CO., INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | MERCK & CO., INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249093-A1 | (3,4-Disubstituted)Propanoic Carboxylates as Sip (Edg) Receptor Agonists | S1PR1, S1PR3, S1PR5 | PPARD 802/4885KDM4C 2303/4885KDM6B 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.