Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.72 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509663 | 0.90 | MRGPRX4 (0.62) | MRGPRX4KDM4CCYP4F2CYP4A11KDM5A | |
| SCHEMBL4510719 | 0.85 | MRGPRX4 (0.66) | MRGPRX4KDM4CCYP4F2CYP4A11KDM5A | |
| SCHEMBL4504246 | 0.84 | MRGPRX4 (0.56) | MRGPRX4KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL22480779 | 0.84 | MRGPRX4 (1.00) | MRGPRX4 | |
| SCHEMBL4512326 | 0.80 | MRGPRX4 (0.63) | MRGPRX4KDM4CCYP4F2CYP4A11KDM5A | |
| SCHEMBL4491985 | 0.79 | MRGPRX4 (0.62) | MRGPRX4KDM4CCYP4F2CYP4A11KDM5A | |
| SCHEMBL22480968 | 0.78 | MRGPRX4 (0.76) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4501168 | 0.78 | MAPT (0.60) | MRGPRX4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4507699 | 0.77 | MRGPRX4 (0.83) | MRGPRX4KDM4CCYP4F2CYP4A11KDM5A | |
| SCHEMBL4500448 | 0.76 | NR4A2 (0.61) | MRGPRX4CYP4F2CYP4A11KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | MRGPRX4 1550/4885KDM4C 554/4885CYP4F2 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.