SCHEMBL4497236

SCHEMBL4497236

CCOC(OC)O[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5931988 0.87 THRB (0.53)
SCHEMBL5931982 0.79
SCHEMBL4504037 0.77 THRB (0.42)
SCHEMBL7067664 0.76
SCHEMBL3179171 0.76
SCHEMBL14706244 0.76
SCHEMBL9873559 0.73 THRB (0.73)
SCHEMBL28143 0.71 THRB (0.59)
SCHEMBL1381944 0.70
SCHEMBL2652 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015123393-A1 NOVEL AMINOALKYLPHOSPHONATE COMPOUNDS AND METHODS USING SAME DREXEL UNIVERISTY (US) 2015-08-20 WO claimed
US-20210309619-A1 ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-10-07 US disclosed
US-11109593-B2 Isoxazolin-5-one derivative and herbicide containing same as active ingredient HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-07 US disclosed
EP-3828176-A1 ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT Hokko Chemical Industry Co., Ltd. (JP) 2021-06-02 EP disclosed
US-20200267985-A1 ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2020-08-27 US disclosed
WO-2020022350-A1 ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT 北興化学工業株式会社 2020-01-30 WO disclosed
WO-2015123393-A1 NOVEL AMINOALKYLPHOSPHONATE COMPOUNDS AND METHODS USING SAME DREXEL UNIVERISTY (US) 2015-08-20 WO disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
EP-1555267-B1 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES OTSUKA PHARMA CO LTD (JP) 2013-01-16 EP disclosed
US-7498350-B2 Oxazolidinones as antibacterial agents ASTRAZENECA AB (SE) 2009-03-03 US disclosed
EP-1575944-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS Astrazeneca AB (SE) 2005-09-21 EP disclosed
EP-1575945-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL Astrazeneca AB (SE) 2005-09-21 EP disclosed
EP-1572687-A1 ANTIBACTERIAL OXAZOLIDINONES AstraZeneca AB (SE) 2005-09-14 EP disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
WO-2004056818-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL ASTRAZENECA AB (SE) 2004-07-08 WO disclosed
WO-2004056816-A1 ANTIBACTERIAL OXAZOLIDINONES ASTRAZENECA AB (SE) 2004-07-08 WO disclosed
WO-2004056819-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ASTRAZENECA AB (SE) 2004-07-08 WO disclosed
WO-2004048350-A2 OXAZOLIDINONES AS ANTIBACTERIAL AGENTS ASTRAZENECA AB (SE) 2004-06-10 WO disclosed
US-4933355-A ALDOSE REDUCTASE INHIBITORS SANKYO COMPANY LIMITED (JP) 1990-06-12 US disclosed
EP-0337819-A1 Thiazole derivatives, their preparation and their use in the treatment of diabetes complications Sankyo Company Limited (JP) 1989-10-18 EP disclosed