Sugi Predict

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SCHEMBL4497306

SCHEMBL4497306

CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(NC(C)=O)c2Cl)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ RAB9A P51151 4/20 0.39
▸ ALDH1A1 P00352 4/20 0.35
▸ LMNA P02545 3/20 0.35
▸ HTT P42858 2/20 0.34
▸ GAA P10253 1/20 0.34
▸ MAPT P10636 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ POLB P06746 2/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ PAX8 Q06710 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4484429 0.88 ALDH1A1 (0.38) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL4505638 0.88 SMN1; SMN2 (0.37) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL4500314 0.86 ALDH1A1 (0.34) ALDH1A1KMT2AMEN1PIK3CDPIK3CA
SCHEMBL8378470 0.86 SMN1; SMN2 (0.36) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL7962639 0.86 SMN1; SMN2 (0.39) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL1963212 0.84 ALDH1A1 (0.39) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL8377450 0.84 SMN1; SMN2 (0.35) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL9448454 0.84 SMN1; SMN2 (0.40) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL8378359 0.83 SMN1; SMN2 (0.34) SMN1; SMN2RAB9AALDH1A1LMNAHTT
SCHEMBL12636827 0.83 RORC (0.36) SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635664-B2 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2009-12-22 — — US disclosed
CN-1256329-C Herbicidally active substituted benzoylpyrazoles BAYER CROPS SCIENCE AG (DE) 2006-05-17 — — CN disclosed
CN-1511143-A Herbicidally active substituted benzoylpyrazoles 拜尔农作物科学股份公司 2004-07-07 — — CN disclosed
US-20040110640-A1 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2004-06-10 — — US disclosed
EP-1395565-A1 HERBICIDAL SUBSTITUTED BENZOYLPYRAZOLES Bayer CropScience AG (DE) 2004-03-10 — — EP disclosed
WO-2002094792-A1 HERBICIDAL SUBSTITUTED BENZOYLPYRAZOLES BAYER CROPSCIENCE AG (DE) 2002-11-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110640-A1 Herbicidal substituted benzoylpyrazoles DDT, GLRX3, CBR3 SMN1; SMN2 4258/4885RAB9A 1588/4885ALDH1A1 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.