Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494728 | 1.00 | P2RY1 (0.37) | P2RY1BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL4496497 | 0.89 | ALDH1A1 (0.34) | P2RY1BRD4MEN1KMT2AALDH1A1 | |
| SCHEMBL4496967 | 0.89 | P2RY1 (0.40) | P2RY1MEN1KMT2ASCN5ASCN9A | |
| SCHEMBL6001687 | 0.88 | PDK1 (0.44) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL4489220 | 0.87 | KMT2A (0.35) | MEN1KMT2AALDH1A1HPGDPDK1 | |
| SCHEMBL4490091 | 0.87 | KMT2A (0.35) | MEN1KMT2AALDH1A1HPGDPDK1 | |
| SCHEMBL4489137 | 0.87 | KMT2A (0.35) | MEN1KMT2AALDH1A1HPGDPDK1 | |
| SCHEMBL4490842 | 0.86 | PDK1 (0.48) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL4482045 | 0.85 | KMT2A (0.43) | P2RY1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4490340 | 0.83 | MEN1 (0.34) | P2RY1MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160815-A1 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | WYETH (US) | 2006-07-20 | — | — | US | claimed |
| US-7563793-B2 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | WYETH (US) | 2009-07-21 | — | — | US | disclosed |
| US-20060160815-A1 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | WYETH (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160815-A1 | Pyrrolo[1,2-a]quinoxalin-5-(4H)-yl)sulfonyls and carbonyls and their use as estrogenic agents | ESR1, GPER1, ESR2 | P2RY1 711/4885BRD4 214/4885MEN1 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.