SCHEMBL449778

SCHEMBL449778

CCCCC([O])O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7342174 1.00
SCHEMBL3185170 0.91
SCHEMBL28631358 0.88 GPR84 (0.56)
SCHEMBL8363305 0.88 GPR84 (0.56)
SCHEMBL27748657 0.88 GPR84 (0.56)
SCHEMBL7290380 0.88 GPR84 (0.56)
SCHEMBL6434519 0.88 GPR84 (0.56)
SCHEMBL6651887 0.88 GPR84 (0.56)
SCHEMBL3175045 0.88
SCHEMBL3186368 0.88 GPR84 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924297-A Methylene-bridged modified cup [3] carbazole derivative and synthetic method and application thereof 沈阳药科大学 2024-04-26 CN claimed
EP-1653960-A4 MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST AMGEN INC (US) 2008-11-26 EP claimed
EP-1653960-A2 MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST AMGEN INC. (US) 2006-05-10 EP claimed
US-20050215526-A1 Melanin concentrating hormone receptor antagonist AMGEN, INC. 2005-09-29 US claimed
WO-2005019167-A2 MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST AMGEN, INC. (US) 2005-03-03 WO claimed
EP-3649194-B1 THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED UV RESISTANCE INEOS STYROLUTION GROUP GMBH (DE) 2024-06-12 EP disclosed
CN-117924297-A Methylene-bridged modified cup [3] carbazole derivative and synthetic method and application thereof 沈阳药科大学 2024-04-26 CN disclosed
WO-2024062086-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS TRINSEO EUROPE GMBH (CH) 2024-03-28 WO disclosed
EP-4342948-A1 FLAME RETARDANT POLYCARBONATE FORMULATIONS Trinseo Europe GmbH (CH) 2024-03-27 EP disclosed
EP-4310138-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-01-24 EP disclosed
EP-4310144-A1 THERMOPLASTIC COMPOSITION AND MOLDED PRODUCT THEREOF Techno-UMG Co., Ltd. (JP) 2024-01-24 EP disclosed
WO-2024013214-A1 POLYCARBONATES WITH HIGH POST-CONSUMER RECYCLE CONTENT TRINSEO EUROPE GMBH (CH) 2024-01-18 WO disclosed
US-4937285-A Use of redox graft polymers to improve the petroleum-resistance of thermoplastic, aromatic polycarbonate and/or polyester carbonate moulding compositions BAYER AKTIENGESELLSCHAFT (DE) 1990-06-26 US disclosed
US-4794141-A BLEND WITH ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1988-12-27 US disclosed
US-4774289-A THERMOPLASTIC RESIN BLEND BAYER AKTIENGESELLSCHAFT (DE) 1988-09-27 US disclosed
US-4746701-A WITH A GRAFT POLYMER AND THERMOPLASTIC VINYL POLYMER BAYER AKTIENGESELLSCHAFT (DE) 1988-05-24 US disclosed
US-4683265-A TOUGHNESS, HEAT STABILITY BAYER AKTIENGESELLSCHAFT (DE) 1987-07-28 US disclosed
US-4192883-A ANTITUSSIVES PIERRE FABRE, S.A. (FR) 1980-03-11 US disclosed
US-4122199-A Amides of pyrrolidinoethylamine which can be used in treatment of coughs PIERRE FABRE S.A. (FR) 1978-10-24 US disclosed
US-3931167-A Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein SCHERING CORPORATION (US) 1976-01-06 US disclosed