SCHEMBL449800

SCHEMBL449800

CCCCCCCCCCCCCCCCC[C]1CCO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
EPHX1 P07099 1/20 0.35
SCD O00767 1/20 0.35
PTGS2 P35354 3/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
ALDH1A1 P00352 2/20 0.34
KCNH2 Q12809 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242339 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1777114 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1176912 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1480092 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL5597049 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL168713 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL11304936 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL2868810 1.00 TSHR (0.38) TSHRTHRBEPHX1SCDPTGS2
SCHEMBL1383985 0.90
SCHEMBL459181 0.88 FAAH (0.44) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3779531-B1 PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME TOKUYAMA CORP (JP) 2024-03-20 EP claimed
CN-114438816-B Oil-in-water type high-carbon alcohol emulsion composition and preparation method thereof 江苏奥斯凯新材料有限公司 2023-03-28 CN claimed
CN-115785319-A Styrene-butadiene latex and preparation method thereof 上海东升新材料有限公司 2023-03-14 CN claimed
CN-114457618-A Heat-resistant coating for paper suction pipe and preparation method thereof 海南必凯水性新材料有限公司 2022-05-10 CN claimed
CN-112480297-A Butylbenzene emulsion for carpet and preparation method thereof 上海昶法新材料有限公司 2021-03-12 CN claimed
CN-111995712-A High-solid-content styrene-butadiene latex as well as preparation method and application thereof 上海东升新材料有限公司 2020-11-27 CN claimed
CN-111304018-A Scrubbing-free car washing powder 北京京蝠环保科技有限公司 2020-06-19 CN claimed
CN-110317538-A Polishing slurry and method of polishing substrate by using the same 三星显示有限公司 2019-10-11 CN claimed
CN-109369844-A A kind of pure-acrylic emulsion and preparation method thereof of super spot-resistant 佛山市顺德区巴德富实业有限公司 2019-02-22 CN claimed
CN-109320169-A A kind of cracking resistance cement pipe pile of photovoltaic and preparation method thereof 盐城欣昌新型建材有限公司 2019-02-12 CN claimed
CN-101808516-A N- (arylamino) sulfonamide derivatives and compositions, including polymorphs, as MEK inhibitors, methods of use, and methods of preparation thereof ARDEA BIOSCIENCES INC 2010-08-18 CN claimed
CN-101760731-A Electroless nickel plating solution composition, flexible printed circuit board and manufacturing method thereof SAMSUNG ELECTRO MECH 2010-06-30 CN claimed
US-7008466-B2 Method for inhibiting hydrate formation BP EXPLORATION OPERATING COMPANY (GB) 2006-03-07 US claimed
EP-1421255-B1 METHOD FOR INHIBITING HYDRATE FORMATION BP EXPLORATION OPERATING (GB) 2005-03-23 EP claimed
US-20040211316-A1 Method for inhibiting hydrate formation BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2004-10-28 US claimed
EP-1421255-A1 METHOD FOR INHIBITING HYDRATE FORMATION BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2004-05-26 EP claimed
WO-2003021078-A1 METHOD FOR INHIBITING HYDRATE FORMATION BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2003-03-13 WO claimed
US-20020125175-A1 Process for reducing the acidity of oil BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2002-09-12 US claimed
EP-1194505-A1 PROCESS FOR REDUCING THE ACIDITY OF OIL BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2002-04-10 EP claimed
WO-2000075262-A1 PROCESS FOR REDUCING THE ACIDITY OF OIL BP EXPLORATION OPERATING COMPANY LIMITED (GB) 2000-12-14 WO claimed