SCHEMBL449816

SCHEMBL449816

COC(CCCN=C=O)CCN=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11807364 0.94
SCHEMBL8937130 0.86
SCHEMBL3809220 0.79
SCHEMBL451004 0.77 DNM1 (0.33)
SCHEMBL2457713 0.74
SCHEMBL16697720 0.74
SCHEMBL868602 0.72 LMNA (0.33)
SCHEMBL27407015 0.72
SCHEMBL10957655 0.72
SCHEMBL22444565 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240141093-A1 Polyol and a Process for the Preparation Thereof BASF SE (DE) 2024-05-02 US claimed
EP-4308629-A1 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2024-01-24 EP claimed
EP-4305085-A1 POLYUREA COPOLYMER BASF SE (DE) 2024-01-17 EP claimed
CN-116997590-A Polyol and process for producing the same 巴斯夫欧洲公司 2023-11-03 CN claimed
CN-116964122-A Polyurea copolymers 巴斯夫欧洲公司 2023-10-27 CN claimed
WO-2022194979-A9 POLYOL AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2023-07-20 WO claimed
US-20230092952-A1 POLYUREA COPOLYMER BASF SE (DE) 2023-03-23 US claimed
US-20230062261-A1 POLYUREA COPOLYMER BASF SE (DE) 2023-03-02 US claimed
CN-114846043-A Polyurea copolymers 巴斯夫欧洲公司 2022-08-02 CN claimed
CN-114829442-A Polyurea copolymers 巴斯夫欧洲公司 2022-07-29 CN claimed
US-9511173-B2 Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio DePuy Synthes Products, Inc. (US) 2016-12-06 US claimed
US-20150231305-A1 Biocompatible, Biodegradable Polyurethane Materials With Controlled Hydrophobic to Hydrophilic Ratio DEPUY SYNTHES PRODUCTS INC (US) 2015-08-20 US claimed
US-9061089-B2 Biocompatible, biodegradable polyurethane materials with controlled hydrophobic to hydrophilic ratio DePuy Synthes Products, Inc. (US) 2015-06-23 US claimed
US-20140023725-A1 Biocompatible, Biodegradable Polyurethane Materials With Controlled Hydrophobic to Hydrophilic Ratio DePuy Synthes Products, LLC (US) 2014-01-23 US claimed
US-8460378-B2 Use as scaffolds, tissue engineering, bone repair, drug delivery; polyurethane derived from biocompatible biodegradable polyols, polyisocyanates, and low molecular weight chain extenders having functionality of two or higher; can be derived from sugar or soy-based ingredients DePuy Sythes Products, LLC (US) 2013-06-11 US claimed
US-20120064025-A1 Quinazolinone Modulators Of Nuclear Receptors EXELIXIS, INC. (US) 2012-03-15 US claimed
EP-1521746-B1 QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS X CEPTOR THERAPEUTICS INC (US) 2011-04-27 EP claimed
US-20080262613-A1 Biocompatible, Biodegradable Polyurethane Materials With Controlled Hydrophobic to Hydrophilic Ratio SYNTHES USA, LLC 2008-10-23 US claimed
WO-2007145399-A1 ASSOCIATIVE POLYMERIC THICKENER AND SURFACTANT AMOREPACIFIC CORPORATION (KR) 2007-12-21 WO claimed
US-4321350-A Process for the catalytic setting of polyurethane molding compositions GAMBRO DIALYSATOREN KG (DE) 1982-03-23 US claimed