SCHEMBL4498413

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2196789	0.82	CDC7 (0.46)	CDC7BRD4LMNACHUKINSR
	SCHEMBL4345912	0.82	IKBKB (0.67)	IKBKBBRD4KDM4EALDH1A1LMNA
	SCHEMBL2199300	0.81	IKBKB (0.50)	IKBKBBRD4KDM4EALDH1A1CHUK
	SCHEMBL2198470	0.80	BRD4 (0.47)	IKBKBCDC7BRD4ALDH1A1LMNA
	SCHEMBL12509787	0.79	KMT2A (0.50)	IKBKBCDC7BRD4KDM4EALDH1A1
	SCHEMBL2198614	0.79	IKBKB (0.47)	IKBKBBRD4KDM4EALDH1A1LMNA
	SCHEMBL2199427	0.78	MAPT (0.55)	IKBKBBRD4KDM4ELMNACHUK
	SCHEMBL4346545	0.78	IKBKB (0.52)	IKBKBBRD4KDM4EALDH1A1CHUK
	SCHEMBL2199409	0.78	IKBKB (0.52)	IKBKBBRD4KDM4EALDH1A1CHUK
	SCHEMBL2197555	0.78	BRD4 (0.49)	CDC7BRD4KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.