Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451024 | 0.89 | FNTA (0.43) | FNTAFNTBTHRBPGGT1BCES2 | |
| SCHEMBL448593 | 0.87 | FNTA (0.50) | FNTAFNTBTHRBPGGT1BCES2 | |
| SCHEMBL9509474 | 0.85 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES2 | |
| SCHEMBL448241 | 0.85 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES2 | |
| SCHEMBL445916 | 0.85 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES2 | |
| SCHEMBL987739 | 0.83 | FFAR3 (0.32) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL15426 | 0.83 | FFAR3 (0.32) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| Acetone SCHEMBL5519061 | 0.82 | FFAR3 (0.31) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| Acetone SCHEMBL5519068 | 0.82 | FFAR3 (0.31) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL30208232 | 0.77 | CES2 (0.31) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-8883928-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | disclosed |
| US-20120065331-A1 | SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS | ALCON INC. (CH) | 2012-03-15 | — | — | US | disclosed |
| US-8079703-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2011-12-20 | — | — | US | disclosed |
| EP-2307190-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011493-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100014047-A1 | Silicone-Containing Polymeric Materials with Hydrolyzable Groups | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-0444508-B1 | Ethylenically unsaturated fluorine-containing urethan derivatives and process for their preparation | HOECHST AG (DE) | 1995-09-13 | — | — | EP | disclosed |
| EP-0444508-A2 | Ethylenically unsaturated fluorine-containing urethan derivatives and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-04 | — | — | EP | disclosed |
| US-4587204-A | PHOTORESISTS, POLYSILOXANE-POLYAMIDES | GENERAL ELECTRIC COMPANY (US) | 1986-05-06 | — | — | US | disclosed |
| US-4515887-A | MODIFIED WITH ISOCYANATOALKYL ACRYLATE | GENERAL ELECTRIC COMPANY (US) | 1985-05-07 | — | — | US | disclosed |