Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448593 | 0.95 | FNTA (0.50) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL9509474 | 0.93 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL445916 | 0.93 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL448241 | 0.93 | FNTA (0.53) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL449846 | 0.89 | FNTA (0.37) | FNTAFNTBTHRBPGGT1BCES1 | |
| SCHEMBL9326072 | 0.81 | KDM1A (0.36) | PTPN1CA1 | |
| SCHEMBL15426 | 0.80 | FFAR3 (0.32) | FNTAFNTBTHRBPGGT1BALDH1A1 | |
| SCHEMBL987739 | 0.80 | FFAR3 (0.32) | FNTAFNTBTHRBPGGT1BALDH1A1 | |
| Acetone SCHEMBL5519061 | 0.79 | FFAR3 (0.31) | FNTAFNTBTHRBPGGT1BALDH1A1 | |
| SCHEMBL28176805 | 0.79 | CES2 (0.39) | FNTAFNTBTHRBPGGT1BCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-8883928-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | disclosed |
| US-20120065331-A1 | SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS | ALCON INC. (CH) | 2012-03-15 | — | — | US | disclosed |
| US-8079703-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2011-12-20 | — | — | US | disclosed |
| EP-2307190-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011493-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100014047-A1 | Silicone-Containing Polymeric Materials with Hydrolyzable Groups | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| EP-0285034-B1 | CURABLE COMPOSITION BASED ON BRANCHED ACRYLATES WITH CARBOXYLIC GROUPS AND/OR BRANCHED ACRYLATES WITH EPOXY GROUPS AND AMINO RESINS | BASF Lacke + Farben AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0291662-B1 | PROCESS FOR THE MANUFACTURE OF BRANCHED ACRYLIC COPOLYMER HAVING POLYMERIZABLE DOUBLE BONDS AND THEIR USE | BASF Lacke + Farben AG (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0373165-A1 | BRANCHED ACRYLATE COPOLYMERISATE WITH POLYMERIZABLE DOUBLE BONDS AND PROCESS FOR MANUFACTURE THEREOF | BASF Lacke + Farben AG (DE) | 1990-06-20 | — | — | EP | disclosed |
| EP-0364450-A1 | HARDENABLE COMPOSITION BASED ON BRANCHED ACRYLATES WITH CARBOXYL GROUPS AND/OR BRANCHED ACRYLATES WITH EPOXY GROUPS AND AMINOPLASTIC RESINS | BASF Lacke + Farben AG (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0181281-B1 | FLUOROALKYLCARBAMYL ACRYLATES AND METHACRYLATES | CIBA-GEIGY AG (CH) | 1989-03-08 | — | — | EP | disclosed |
| EP-0291662-A1 | Process for the manufacture of branched acrylic copolymer having polymerizable double bonds and their use | BASF Lacke + Farben AG (DE) | 1988-11-23 | — | — | EP | disclosed |
| WO-1988007555-A1 | BRANCHED ACRYLATE COPOLYMERISATE WITH POLYMERIZABLE DOUBLE BONDS AND PROCESS FOR MANUFACTURE THEREOF | BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) | 1988-10-06 | — | — | WO | disclosed |
| WO-1988007565-A1 | HARDENABLE COMPOSITION BASED ON BRANCHED ACRYLATES WITH CARBOXYL GROUPS AND/OR BRANCHED ACRYLATES WITH EPOXY GROUPS AND AMINOPLASTIC RESINS | BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) | 1988-10-06 | — | — | WO | disclosed |
| EP-0285034-A1 | Curable composition based on branched acrylates with carboxylic groups and/or branched acrylates with epoxy groups and amino resins | BASF Lacke + Farben AG (DE) | 1988-10-05 | — | — | EP | disclosed |
| EP-0177447-B1 | DIPERFLUOROALKYL CARBAMYL ACRYLATES AND METHACRYLATES | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |
| EP-0181281-A1 | Fluoroalkylcarbamyl acrylates and methacrylates | CIBA-GEIGY AG (CH) | 1986-05-14 | — | — | EP | disclosed |
| EP-0177447-A1 | Diperfluoroalkyl carbamyl acrylates and methacrylates | CIBA-GEIGY AG (CH) | 1986-04-09 | — | — | EP | disclosed |