Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449896 | 0.99 | TBXAS1 (0.32) | TBXAS1 | |
| SCHEMBL5006417 | 0.75 | TBXAS1 (0.41) | TBXAS1 | |
| SCHEMBL1217777 | 0.73 | TBXAS1 (0.38) | TBXAS1 | |
| SCHEMBL7543889 | 0.71 | FFAR1 (0.40) | TBXAS1 | |
| SCHEMBL4581374 | 0.71 | FFAR1 (0.40) | TBXAS1 | |
| SCHEMBL329975 | 0.71 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL2486065 | 0.69 | TET2 (0.39) | TBXAS1 | |
| SCHEMBL8647496 | 0.69 | KDM4C (0.47) | TBXAS1 | |
| SCHEMBL14936541 | 0.69 | KDM4C (0.47) | TBXAS1 | |
| SCHEMBL920756 | 0.69 | KDM4C (0.47) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096025-B2 | Silicone hydrogel lenses with convertible comfort agents | NOVARTIS AG (CH) | 2015-08-04 | — | — | US | disclosed |
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | disclosed |
| US-8883928-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2014-11-11 | — | — | US | disclosed |
| EP-2307189-B1 | SILICONE HYDROGEL CONTACT LENSES WITH CONVERTIBLE COMFORT AGENTS | NOVARTIS AG (CH) | 2014-06-04 | — | — | EP | disclosed |
| US-20130127077-A1 | SILICONE HYDROGEL LENSES WITH CONVERTIBLE COMFORT AGENTS | NOVARTIS AG (CH) | 2013-05-23 | — | — | US | disclosed |
| US-8357760-B2 | Silicone hydrogel contact lenses with convertible comfort agents | NOVARTIS AG (CH) | 2013-01-22 | — | — | US | disclosed |
| US-20120065331-A1 | SILICONE-CONTAINING POLYMERIC MATERIALS WITH HYDROLYZABLE GROUPS | ALCON INC. (CH) | 2012-03-15 | — | — | US | disclosed |
| US-8079703-B2 | Silicone-containing polymeric materials with hydrolyzable groups | NOVARTIS AG (CH) | 2011-12-20 | — | — | US | disclosed |
| EP-2307190-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| EP-2307189-A1 | SILICONE HYDROGEL CONTACT LENSES WITH CONVERTIBLE COMFORT AGENTS | Novartis AG (CH) | 2011-04-13 | — | — | EP | disclosed |
| WO-2010011493-A1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| WO-2010011492-A1 | SILICONE HYDROGEL CONTACT LENSES WITH CONVERTIBLE COMFORT AGENTS | NOVARTIS AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| US-20100014047-A1 | Silicone-Containing Polymeric Materials with Hydrolyzable Groups | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |
| US-20100016514-A1 | Silicone Hydrogel Contact Lenses with Convertible Comfort Agents | ALCON INC. (CH) | 2010-01-21 | — | — | US | disclosed |