SCHEMBL4499103

SCHEMBL4499103

C=COc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.53
AKR1C3 P42330 1/20 0.50
MAPT P10636 5/20 0.47
MAPK1 P28482 2/20 0.47
GAA P10253 1/20 0.47
DRD2 P14416 1/20 0.46
DRD1 P21728 1/20 0.46
DRD3 P35462 1/20 0.46
ALDH1A1 P00352 2/20 0.45
ABCB1 P08183 5/20 0.43
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 1/20 0.42
AKT1 P31749 1/20 0.42
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
CDC25B P30305 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109985 0.89 ELANE (0.47) ELANEMAPTGAAALDH1A1KDM4E
SCHEMBL6151817 0.84 ELANE (0.54) ELANEAKR1C3MAPTMAPK1GAA
SCHEMBL32687438 0.83 KDM4E (0.56) AKR1C3MAPTALDH1A1KDM4EHSD17B10
SCHEMBL4209791 0.83 KDM4E (0.56) AKR1C3MAPTALDH1A1KDM4EHSD17B10
SCHEMBL3121170 0.82 MAPT (0.60) ELANEAKR1C3MAPTMAPK1GAA
SCHEMBL3115035 0.82 KMT2A (0.57) ELANEMAPTMAPK1GAAALDH1A1
SCHEMBL3113786 0.81 HPGD (0.45) ELANEMAPTGAAALDH1A1KDM4E
SCHEMBL27861172 0.79 ELANE (0.57) ELANEAKR1C3MAPTMAPK1GAA
SCHEMBL29805146 0.79 ELANE (0.58) ELANEAKR1C3MAPTMAPK1GAA
SCHEMBL474832 0.79 ELANE (0.58) ELANEAKR1C3MAPTMAPK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518021-B2 Aromatic vinyl ether compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-04-14 US disclosed
EP-1478671-B1 UV-CROSSLINKABLE COPOLYMERS BASF AG (DE) 2007-09-12 EP disclosed
US-7091296-B2 UV-crosslinkable copolymers BASF AKTIENGESELLSCHAFT (DE) 2006-08-15 US disclosed
US-20050080213-A1 copolymerizable photoinitiators comprising ortho-, meta-, or para-vinyl ethers of acetophenone or benzophenone; addition copolymerization in solution; binders and pressure sensitive adhesives; high cohesion and adhesion; chemical resistance to hydrolysis; storage stability BASF AKTIENGESELLSHAFT (DE) 2005-04-14 US disclosed
EP-1478671-A1 UV-CROSSLINKABLE COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2004-11-24 EP disclosed
US-20040181098-A1 Aromatic vinyl ether compounds EMORY UNIVERSITY 2004-09-16 US disclosed
EP-1413568-A2 Aromatic vinyl ether compounds Daicel Chemical Industries, Ltd. (JP) 2004-04-28 EP disclosed
WO-2003070792-A1 UV- CROSSLINKABLE COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2003-08-28 WO disclosed
EP-0088842-B1 ORGANOPOLYSILOXANE PHOTOSENSITIZERS AND METHODS FOR THEIR PREPARATION Toray Silicone Company Limited (JP) 1986-01-02 EP disclosed
US-4467082-A Organopolysiloxane photosensitizers and methods for their preparation DOW CORNING CORPORATION (US) 1984-08-21 US disclosed
EP-0088842-A1 Organopolysiloxane photosensitizers and methods for their preparation Toray Silicone Company Limited (JP) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040181098-A1 Aromatic vinyl ether compounds SUV39H2, SUV39H1, RAVER1 ELANE 2856/4885AKR1C3 1065/4885MAPT 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.