SCHEMBL3113786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3109985	0.91	ELANE (0.47)	HPGDLMNAALOX15CYP3A4LIG1
	SCHEMBL4499103	0.81	ELANE (0.53)	HPGDLMNAALOX15CYP3A4KDM4E
	SCHEMBL4063222	0.79	LIG1 (0.61)	HPGDLMNAARALOX15HIF1A
	SCHEMBL32687438	0.78	KDM4E (0.56)	HPGDLMNAALOX15CYP1A2KDM4E
	SCHEMBL4209791	0.78	KDM4E (0.56)	HPGDLMNAALOX15CYP1A2KDM4E
	SCHEMBL1883142	0.77	TSHR (0.50)	HPGDLMNAALOX15HIF1ACYP3A4
	2,2'-Dihydroxybenzphenone SCHEMBL18422	0.77	HPGD (0.67)	HPGDLMNAARALOX15HIF1A
	2,2'-Dihydroxybenzphenone SCHEMBL29572496	0.77	HPGD (0.67)	HPGDLMNAARALOX15HIF1A
	SCHEMBL4060271	0.77	LMNA (0.62)	HPGDLMNAARALOX15HIF1A
	SCHEMBL8608640	0.77	CYP3A4 (0.43)	HPGDLMNACYP1A2CYP3A4LIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.